oral mucosa :) Flashcards

1
Q

normal appearance (variations on the normal)

A
fissured tongue (deep fissured)
sebaceous glands (white/yellow spots)
lingual tonsils (enlarged)
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2
Q

what is manageable in practise

A

amalgam tattoo
candida infection
leukoedema
black hairy tongue

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3
Q

amalgam tatto

A

amalgam trapped in mucosa of mouth

extraction of a molar with amalgam, teeth crumble and fragments can get trapped

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4
Q

candida infection

A

middle of tongue is depapilated

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5
Q

leukodema

A

white/grey lesions of mucosa

if stretched will disappear

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6
Q

functions of oral mucosa

A

protection
secretion (minor salivary glands in mouth)
sensation

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7
Q

oral muscosa protection function

A

resistance to abrasion

permeability barrier

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8
Q

structure of the oral music layers

A

epithelium
lamina propria
submucosa

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9
Q

epithelium of oral muscoa

A

stratified squamous epithelium

may be keratinised

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10
Q

lamina propira

A

dense connective tissue

underneath the epithelium

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11
Q

submucora

A

loose CT and glands

inc fat, minor salivary glands

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12
Q

layers in histology of hard palate

A

keratinised ayer
granular laer
spinous layer
basal layer (proliferaties and replaces the cells at the top)

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13
Q

what does the granular layer contain

A

keratinylain granules

membrane coating granules

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14
Q

keratohyalin granules

A

bind cytokeratin filaments to form keratin

cytokeratin found in cytoplasm

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15
Q

membrane coating granules

A

coat cell membranes to produce waterproof barriers

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16
Q

structure of non keratinised epithelium

A

basal
prickle cell
superficial layer

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17
Q

epithelial cell attatchemns

A

desomsomes - attach to epithelium cells

hemidesmosomes - attach to basement membrane

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18
Q

diseases that can affect the attachments in epithelial layers

A

pemphigus

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19
Q

pemphigus and clinical observations

A

auto immune disease
autoantibodies produces which attack mucosa by attacking desmosomes (epithelium un zips)

clinical
-erosions and ulcers in moth
epithelium can peel apart during eating

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20
Q

epithelial clear cells

A

melanocytes
merkel cells
langerhans cells

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21
Q

melanocytes

A

melanin producing cells

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22
Q

merkel cells

A

sensory receptors

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23
Q

langerhans cells

A

antigen presenting cells

when epxosed to foreign molecule, come out of epithelium into lymph nodes to present antigen to T helper

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24
Q

melanin

A

found in basal third of epithelium
brown/black
melanocytes have dendritic processes that distribute melanosoma to other cells

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25
how is melanin transfered to adjacent keratinocytes
via membrane bound melanosomes
26
malignant melanoma
rate brown/balck irregular region often spreads to lymph nodes in the neck
27
where are langerhans cells found
spinous layer
28
leukocytes
found in epithelium | lymphocytes and neutrofils
29
Langerhans cell histiocytosis
rare cancer proliferation of langerhams cells - bone has largely gone, teeth essentially floating
30
types of oral muscoa
masticatory lining gustatory specilaised
31
masticatory muscosa
areas of high abration | e.g. hard palate and gingica
32
lining muscos
areas nit subject to high abration i.e. floor of mouth./vertral tongue
33
gustatory lining muscsa
specliased for resistance by papillae and cast buds e.g. dorsal tongue
34
specialised mucsoa
does not fit into other catagoies | i.e. vermillion border, junctional epithelium
35
what is the muscle liken the palatal vault
pale | no submuscoa so bound to underlying bone
36
where can you get minor glands which can become tumourised
lateral palate
37
histology of masticatory epithelium
parakeratinised stratifised squamous eptuehlium deep rate ridges o allow anchoring with CT dense lamina propria
38
where is the mucogingical junction
transition masticatory to the lining mucosa
39
free gingival groove
junction between attached and free gingivae
40
what is the marginal gingiva also known as
free ginigva
41
what is attached gingiva attached to
attached to bone
42
junctional epithelium
2 basal lamina/basment membrane - once on deep and other on superficial side adjacent to enamel or cementum wide intracellular spaces
43
what is at junctional epithelim
crevicular fluid
44
crevicular fluid
may contain leukocytes contains secretory IgA clears out and neutralises bacteria Serum exudate through junctional epithelial cells
45
lining on the buccal mucosa
lining mucosa stratified squamous non keratinesed - may be along occlusal plane due to biting or grinding dense lamina proproa sub mucosa - loose and minor salivary glands may contain sebaceous glands on occlusal plane
46
soft palate oral side
lining muscosa no keratinsed minor mucous salivary glands submucosa blends with underling muscles
47
vermillion border
where skin meets the lip transitional zone between hairy skin and lining oral mucosa no appendages thin lamina propria bound to underlain muscle
48
what is found in a pilosebacous unit
hair follicle sebaceous gland erector pilli muscle
49
what mucosa is on the tongue
gustatory musocsa
50
papillae on the tongue
filiform fungiform circumvallate foliate
51
filiform papillae
most numerous | mechiniscal abrasion and mastication of food
52
fungiform papillae
round cirucalr taste
53
cimcumvallate
found along sulcus terminals marking 1/3 tongue v shape taste
54
foliate
edges of posterior tongue | taste
55
filiform histology
heavily keratinised narrow core of CT appear spikey
56
fungiform papillae histology
non keratinised | taste buds laterally
57
circumvallate papillae histology
``` large deep sulcus non keratinised tastebuds on lateral surfaces serous salivary glands beneath sulk ```
58
ventral surface of the tongue
thin non keratinised lining muscosa loose submocosa very permeable
59
problems with the tomgue
glossitis | black hairy tongue
60
glossitis and causes
smooth and shiny soreness and during causes - vitamin deficiency candidal infections
61
black hairy tongue
associated with those on soft diets long elongated papillae can get stained during smoking/food stains papillae not shedding as usual
62
treatment for black hairy tongue
tongue scraper to remove the surface
63
age changes in oral muscosa
muscosa may appear atrophic and smoother decrease in elasticity prominence of fordyce spots varicosities ventral surface tongue (more prominent veins)
64
variations on normal mucosa
leukodema geographic tome fordyce spots
65
geographic tongue
isilands of erythema with white borders | mild soreness/asymtompatic
66
fordyce spots
ectopic sebaceous glands | symptomatic