oral mucosa :) Flashcards
normal appearance (variations on the normal)
fissured tongue (deep fissured) sebaceous glands (white/yellow spots) lingual tonsils (enlarged)
what is manageable in practise
amalgam tattoo
candida infection
leukoedema
black hairy tongue
amalgam tatto
amalgam trapped in mucosa of mouth
extraction of a molar with amalgam, teeth crumble and fragments can get trapped
candida infection
middle of tongue is depapilated
leukodema
white/grey lesions of mucosa
if stretched will disappear
functions of oral mucosa
protection
secretion (minor salivary glands in mouth)
sensation
oral muscosa protection function
resistance to abrasion
permeability barrier
structure of the oral music layers
epithelium
lamina propria
submucosa
epithelium of oral muscoa
stratified squamous epithelium
may be keratinised
lamina propira
dense connective tissue
underneath the epithelium
submucora
loose CT and glands
inc fat, minor salivary glands
layers in histology of hard palate
keratinised ayer
granular laer
spinous layer
basal layer (proliferaties and replaces the cells at the top)
what does the granular layer contain
keratinylain granules
membrane coating granules
keratohyalin granules
bind cytokeratin filaments to form keratin
cytokeratin found in cytoplasm
membrane coating granules
coat cell membranes to produce waterproof barriers
structure of non keratinised epithelium
basal
prickle cell
superficial layer
epithelial cell attatchemns
desomsomes - attach to epithelium cells
hemidesmosomes - attach to basement membrane
diseases that can affect the attachments in epithelial layers
pemphigus
pemphigus and clinical observations
auto immune disease
autoantibodies produces which attack mucosa by attacking desmosomes (epithelium un zips)
clinical
-erosions and ulcers in moth
epithelium can peel apart during eating
epithelial clear cells
melanocytes
merkel cells
langerhans cells
melanocytes
melanin producing cells
merkel cells
sensory receptors
langerhans cells
antigen presenting cells
when epxosed to foreign molecule, come out of epithelium into lymph nodes to present antigen to T helper
melanin
found in basal third of epithelium
brown/black
melanocytes have dendritic processes that distribute melanosoma to other cells
how is melanin transfered to adjacent keratinocytes
via membrane bound melanosomes
malignant melanoma
rate
brown/balck irregular region
often spreads to lymph nodes in the neck