oral mucosa :) Flashcards

1
Q

normal appearance (variations on the normal)

A
fissured tongue (deep fissured)
sebaceous glands (white/yellow spots)
lingual tonsils (enlarged)
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2
Q

what is manageable in practise

A

amalgam tattoo
candida infection
leukoedema
black hairy tongue

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3
Q

amalgam tatto

A

amalgam trapped in mucosa of mouth

extraction of a molar with amalgam, teeth crumble and fragments can get trapped

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4
Q

candida infection

A

middle of tongue is depapilated

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5
Q

leukodema

A

white/grey lesions of mucosa

if stretched will disappear

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6
Q

functions of oral mucosa

A

protection
secretion (minor salivary glands in mouth)
sensation

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7
Q

oral muscosa protection function

A

resistance to abrasion

permeability barrier

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8
Q

structure of the oral music layers

A

epithelium
lamina propria
submucosa

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9
Q

epithelium of oral muscoa

A

stratified squamous epithelium

may be keratinised

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10
Q

lamina propira

A

dense connective tissue

underneath the epithelium

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11
Q

submucora

A

loose CT and glands

inc fat, minor salivary glands

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12
Q

layers in histology of hard palate

A

keratinised ayer
granular laer
spinous layer
basal layer (proliferaties and replaces the cells at the top)

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13
Q

what does the granular layer contain

A

keratinylain granules

membrane coating granules

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14
Q

keratohyalin granules

A

bind cytokeratin filaments to form keratin

cytokeratin found in cytoplasm

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15
Q

membrane coating granules

A

coat cell membranes to produce waterproof barriers

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16
Q

structure of non keratinised epithelium

A

basal
prickle cell
superficial layer

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17
Q

epithelial cell attatchemns

A

desomsomes - attach to epithelium cells

hemidesmosomes - attach to basement membrane

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18
Q

diseases that can affect the attachments in epithelial layers

A

pemphigus

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19
Q

pemphigus and clinical observations

A

auto immune disease
autoantibodies produces which attack mucosa by attacking desmosomes (epithelium un zips)

clinical
-erosions and ulcers in moth
epithelium can peel apart during eating

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20
Q

epithelial clear cells

A

melanocytes
merkel cells
langerhans cells

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21
Q

melanocytes

A

melanin producing cells

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22
Q

merkel cells

A

sensory receptors

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23
Q

langerhans cells

A

antigen presenting cells

when epxosed to foreign molecule, come out of epithelium into lymph nodes to present antigen to T helper

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24
Q

melanin

A

found in basal third of epithelium
brown/black
melanocytes have dendritic processes that distribute melanosoma to other cells

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25
Q

how is melanin transfered to adjacent keratinocytes

A

via membrane bound melanosomes

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26
Q

malignant melanoma

A

rate
brown/balck irregular region
often spreads to lymph nodes in the neck

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27
Q

where are langerhans cells found

A

spinous layer

28
Q

leukocytes

A

found in epithelium

lymphocytes and neutrofils

29
Q

Langerhans cell histiocytosis

A

rare cancer
proliferation of langerhams cells
- bone has largely gone, teeth essentially floating

30
Q

types of oral muscoa

A

masticatory
lining
gustatory
specilaised

31
Q

masticatory muscosa

A

areas of high abration

e.g. hard palate and gingica

32
Q

lining muscos

A

areas nit subject to high abration i.e. floor of mouth./vertral tongue

33
Q

gustatory lining muscsa

A

specliased for resistance by papillae and cast buds e.g. dorsal tongue

34
Q

specialised mucsoa

A

does not fit into other catagoies

i.e. vermillion border, junctional epithelium

35
Q

what is the muscle liken the palatal vault

A

pale

no submuscoa so bound to underlying bone

36
Q

where can you get minor glands which can become tumourised

A

lateral palate

37
Q

histology of masticatory epithelium

A

parakeratinised stratifised squamous eptuehlium
deep rate ridges o allow anchoring with CT
dense lamina propria

38
Q

where is the mucogingical junction

A

transition masticatory to the lining mucosa

39
Q

free gingival groove

A

junction between attached and free gingivae

40
Q

what is the marginal gingiva also known as

A

free ginigva

41
Q

what is attached gingiva attached to

A

attached to bone

42
Q

junctional epithelium

A

2 basal lamina/basment membrane
- once on deep and other on superficial side
adjacent to enamel or cementum
wide intracellular spaces

43
Q

what is at junctional epithelim

A

crevicular fluid

44
Q

crevicular fluid

A

may contain leukocytes
contains secretory IgA
clears out and neutralises bacteria
Serum exudate through junctional epithelial cells

45
Q

lining on the buccal mucosa

A

lining mucosa
stratified squamous
non keratinesed
- may be along occlusal plane due to biting or grinding
dense lamina proproa
sub mucosa - loose and minor salivary glands
may contain sebaceous glands on occlusal plane

46
Q

soft palate oral side

A

lining muscosa no keratinsed
minor mucous salivary glands
submucosa blends with underling muscles

47
Q

vermillion border

A

where skin meets the lip
transitional zone between hairy skin and lining oral mucosa
no appendages
thin lamina propria bound to underlain muscle

48
Q

what is found in a pilosebacous unit

A

hair follicle
sebaceous gland
erector pilli muscle

49
Q

what mucosa is on the tongue

A

gustatory musocsa

50
Q

papillae on the tongue

A

filiform
fungiform
circumvallate
foliate

51
Q

filiform papillae

A

most numerous

mechiniscal abrasion and mastication of food

52
Q

fungiform papillae

A

round
cirucalr
taste

53
Q

cimcumvallate

A

found along sulcus terminals marking 1/3 tongue
v shape
taste

54
Q

foliate

A

edges of posterior tongue

taste

55
Q

filiform histology

A

heavily keratinised
narrow core of CT
appear spikey

56
Q

fungiform papillae histology

A

non keratinised

taste buds laterally

57
Q

circumvallate papillae histology

A
large 
deep sulcus
non keratinised
tastebuds on lateral surfaces
serous salivary glands beneath sulk
58
Q

ventral surface of the tongue

A

thin non keratinised lining muscosa
loose submocosa
very permeable

59
Q

problems with the tomgue

A

glossitis

black hairy tongue

60
Q

glossitis and causes

A

smooth and shiny
soreness and during

causes
- vitamin deficiency
candidal infections

61
Q

black hairy tongue

A

associated with those on soft diets
long elongated papillae
can get stained during smoking/food stains
papillae not shedding as usual

62
Q

treatment for black hairy tongue

A

tongue scraper to remove the surface

63
Q

age changes in oral muscosa

A

muscosa may appear atrophic and smoother
decrease in elasticity
prominence of fordyce spots
varicosities ventral surface tongue (more prominent veins)

64
Q

variations on normal mucosa

A

leukodema
geographic tome
fordyce spots

65
Q

geographic tongue

A

isilands of erythema with white borders

mild soreness/asymtompatic

66
Q

fordyce spots

A

ectopic sebaceous glands

symptomatic