embroyonic development :) Flashcards

1
Q

what does human development start out as

A

oocyte (single cell)

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2
Q

how long does human development take

A

38 wks

3 trimesters

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3
Q

what are the 3 trimester stages called

A

pre-embryonic period
embryonic period
fetal period

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4
Q

what occurs in pre embroyonic period and time

A

embryonic germ layers formed(make the basic tissues needed to form the organism)
0-2.5 wks

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5
Q

embryonic period and time

A

2.5-8wks

rudiments of most organims and tissues develop

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6
Q

fetal period and time

A

8wk to 9mn
rudiments grow and mature
called a foetus

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7
Q

what has to form early on

A

heart and CVS system to push nutrients around the body

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8
Q

what can embroyonic cells do

A

divide
death (remove cell by apotosis)
fixed/motile (chemical gradients may cause movements)
shape change(may be needed to form polarised cells)
specilalise

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9
Q

what is cleavage

A

series of cell divisions that subdivides the cytoplasm

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10
Q

what occurs in pre embryonic development

A

cleavage
morula formation
blastocyte formation

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11
Q

during cleavage…

A

size of the blastomere stays the same

no cells increases

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12
Q

what is a morula

A

ball of 16 cells

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13
Q

what happens to the morula

A

takes up fluid and hollows out to form a blastocyte

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14
Q

what forms the extra emmbryonic structres

A

trophoblast

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15
Q

what surrounds the blastocyte after 5/6 days and purpose

A

zona pallucida

prevent sperm entering early

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16
Q

what is found in the blastocyte

A

inner cell mass (figure of 8 shape)

form the embyro

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17
Q

what does the pre embryo appear as

A

bilaminar disk (2 cell layers)

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18
Q

what are the 2 layers of the pre embryo

A

epiblast (upper layer, columnar cells)

hypoblast (lower layer, cuboidal cells)

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19
Q

what occurs after the pre embryo is formed

A

gastrulation

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20
Q

what is gastrulation

A

where the 3rd germ layer is formed

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21
Q

gastrulation process steps

A

epiblast cells move towards the primitive streak(accross the embryonic disk) and invaginate to displace the hypoblast cells
some epilast cells detach and move betwee the epiblast and hypoblast layer
notochord fomration

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22
Q

what does the primitive streak do

A

estavlished the cranial/caudal ends and the right/left of embryo

23
Q

what are the three embryonic layers

A

ectoderm (outer)
mesoderm (middle)
endoderm (inner)

24
Q

what are the three embryonic layers in terms of abilty to speclise

A

mulipotent

25
what does gastrulation allow
basic framework of embryo formed | all adult systems reconisable at 8wks
26
what happens after gastrulation
organonesis | 1st step within that is neuralation
27
what happens in neuralation
formation of neural tube grt the CNS
28
as the CNS develops what else develops
another germ layer (ectomesoderm)
29
neuralation steps
ectoderm thickens in midline(above the notochord) and grows caudally a crease develops along the axis of the neural plate by invagination neural folds move together and fuse to form neurla tube neural crest ells detatch to form the neural crest
30
where are neural crest cells and what does the neural crest contibute to
on the crest of the neural groove migrating to the mesoderm | formation of peripheral NS
31
what do crainial neural cells differentaite into
craniofacil cartialge and bones
32
what do ectoderm cells form
epidermis hair mucus epithelium (ie nose mouth)
33
what do mesoderm cells form
skeletal/musular components
34
what do endoderm cells form
mucus epithelium (digestive and respiratory)
35
what do neuroderm cells form
CNS and peripheral nerves
36
what does the embryo have at 3.5 wks
cranial and caudal ends | pharyngeal arches
37
how many pairs of pharyngeal arches are there
6 pairs in neck 5 never forms 456 fuse separated by cleft (externally)
38
what are the arches called
1 - mandibular 2 - hyoid 3 - glossopharyngeal
39
what are arches separated by internally
pouches
40
what is found in each arch
``` cartilage artyer mesoderm component cranial nerves skeletal component ```
41
what does the Hox gene do
each of muscle derived from the arch is innervated by the nerve that arises from the arch
42
pharyngeal arch nerves
1 - trigeminal V 2- facial VII 3 - glossopharyngeal IX 4- vagus X
43
what forms the external ear, iddle ear and auditory tube
first cleft - external | corresponding pouch - middle and tube
44
where do arch deformities mainly occur
1st arch
45
deformities of 1st arch symptoms
``` underdeveloped mandible (class II occlusion) malformed external ears absent/reduced malleus/incus ```
46
muscle derivaitves 1st arch
muscles of mastication - myelohyoid - anterior belly of digastric and tensor veil palatini
47
muscle derivatives 2nd arch
stylohyoid | posterior belly of digasttic and stapedius
48
muscle derivatives 3rd arch
stylopharyngeus
49
muscle derivatives 4th arch
pharyngeal constricutors soft palate LTP intrinsic muscles of larynx
50
skeletal derivatives 1st arch
meckels cartilage (until mandible forms) malleus incus
51
skeletal derivatives 2nd arch
stapes | styloud process
52
skeletal derivatives 3rd
hyoid bone
53
skeletal derivatives 4th
laryngeal cartilages | epiglottis