Chapter 5 structure and function of DNA Flashcards
chromosomes consist of
5-carbon sugar: deoxyribose
phosphate group
1 of 4 nucleotide bases
DNA nucleotide bases
cytosine
thymine
guanine
adenine
histone
proteins that the DNA helix winds around to form nucleosomes.
chromatin
DNA + histones
replication orgins
specific places along chromatin where initiator proteins attach to pull apart DNA strands and begin replication.
DNA polymerase
enzyme complex that binds to single separated stand of DNA to being forming new complimentary strand.
also proofreads new strand for errors.
DNA replication goes from
3’ to 5’
meaning there is a
leading strand: 3’-5’
lagging strand: 5’-3’
characteristics of cell come from
proteins and enzymes
amino acids
specific sequences that make up proteins to dictate structure and activity
codon
3 nucleotides that code for amino acids
stop codon
signal end of protein
RNA bases
cytosine
uracil
guanine
adenine
mRNA
synthesized from DNA template in transcription
carries protein code to cytoplasm for protein manufacturing
rRNA
ribosomal RNA
tRNA
carries amino acids due to be united to form proteins.
codons and amino acids do not recognize one another, tRNA translates
transcription
mRNA synthesized from a single stranded DNA template
-sense strand: contains desired gene sequense
gene transcription begins when
RNA-polymerase enyzme binds to a promoter region upstream of desired gene
- matches RNA bases to DNA template
intron
sections of template that need to be removed before being translated.
exons
portion of mRNA that will be translated
mRNA directs synthesis of
proteins with tRNA and ribosomes in the cytoplasm
translation
mRNA used to synthesize protein
ribosome part in protein synthesis
needed to align mRNA and tRNA
catalyze peptide bonds holding aminos together
gene expression can be regulated at
each step in DNA to RNA to protein synthesis
transcriptional control
gene regulatory proteins control transcription by binding in major groove of DNA near promoter sequence.
can be positive (enhance transcription)
negative (inhibit transcription)
Mechanisms of development (4)
cell proliferation
cell specialization
cell to cell interaction
cell movement and migration