Cardiac excitability/electro Flashcards
Cardiac action potential has 5 phases
0-4
cardiac action potential phase 0
membrane potential -> threshold
- voltage gated Na channels open -> influx
- depolarization: upstroke
cardiac action potential phase 1
small repolarization: closure of Na channels
transient efflux of K+
cardiac action potential phase 2
plateau phase
- Ca influx offset by K+ efflux
cardiac action potential phase 3
rapid return to resting potential
- closure of Ca channels
- K efflux
cardiac action potential phase 4
period of time between AP no change in membrane voltage
SA node
pacemaker: 60-80 BPM
origin of impulse
upper Right ventricle
AV node
spontaneous depolarization: 40-60 BPM
bottom of Right Atria, just above R. ventricle
Purkinje fibers
spontaneous depolarization: 15-40 BPM
innervate muscle around ventricles
bundle branches
between AV node and purkinje fibers go down interventricular septum
overdrive suppression
faster pacemakers suppress automatic discharge of slower pacemakers
P wave
atrial depolarization
QRS
ventricular depolarization
T wave
Ventricular repolarizatoin
S
depolarization of ventricular base