antiarytmika Flashcards

1
Q

klass 1

A

membranstabiliserande

Na-kanaler

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2
Q

klass Ia

A

ex. disopyramid
- långsam depol
- längre repol

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3
Q

klass Ib

A

långsam depol
förkortad repol

  • lidokain
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4
Q

klass Ic

A

flekainid

långsam depol

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5
Q

hur verkar flekainid

A

hämmar Na flöde under AK

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6
Q

klass II

A

betablockad

  • fördröjer spontan diastolisk depolarisation i PM-celler
  • t.ex. metoprolol, bisoprolol
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7
Q

klass III

A

förlängd repolarisation

- t.ex. amiodarone

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8
Q

klass IV

A

Ca blockad
- fördröjer depolarisation i PM-celler

  • verapamil
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9
Q

hur verkar amiodarone

A

hämning av K-kanal som förlänger AP (repolarisation).

reducerar sinus-automaticitet

påverkar SA, förmak och nodal retledning

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