9.3 Glomerular Filtration Rate Flashcards
1
Q
Why does it make sense that sympathetic stimulation causes podocytes to contract and become less permeable?
A
- Sympathetic stimulation increases heart rate and blood pressure
- Without contraction of podocytes, GFR would increase dramatically during this increase
2
Q
What is average glomerular filtration rate for a 20 year old?
A
90-140mL/min (normal distribution)
3
Q
Is GFR same for men and women?
A
No. Usually lower in women, since they are smaller.
4
Q
Does GFR change with age?
A
Yes. 10% of renal function is lost for every ten years after 20.
5
Q
Why is it important to regulate GFR?
A
- Homeostasis
- Electrolyte balance
- Fluid balance
- Excretion of waste products
6
Q
Does GFR change with changes in blood pressure?
A
Typically not, within autoregulatory range
7
Q
PRAC: Where are the most common sites of lodgement of kidney stones within the ureter?
A
- Ureteropelvic junction
- Crossing external iliac vessels
- Ureter transverses bladder wall
