2.10 Tissue Level of Organisation - Epithelial; Connective; Muscle; Nervous Tissues Flashcards

1
Q

Epithilium classification: number of layers

A

One layer: simple
>1 layers: stratified

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2
Q

Epithilium classification: cell shape on apical surface

A

Flat: squamous
Cube-like: Cuboidal
Column-like: Columnal

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3
Q

Common function of simple squamous epithilium

A
  • Lines blood vessels and air sacs of lungs
  • Permits exchange of nutrients, wastes, and gases
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4
Q

Common function of simple cuboidal epithilium

A
  • Lines kidney tubules and glands
  • Secretes and reabsorbs water and small molecules
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5
Q

Common function of Simple columnar epithilium. Therefore, where would it commonly be located?

A
  • Lines most digestive organs
  • Absorbs nutrients, produces mucus (have microvilli)
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6
Q

Common function of stratified squamous epithilium

A
  • Outer layer of skin, mouth, vagina
  • Protects against abrasion, drying out, infection
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7
Q

Common function of stratified cuboidal epithilium

A
  • Lines ducts of sweat glands
  • Secretes water and ions
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8
Q

Common function of stratified/psuedostratified columnar epithilium

A
  • Lines epididymus, mammary glands, larynx
  • Secretes mucus
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9
Q

What are the two types of epithelium?

A
  • Surface: covers and lines the inside and outside surfaces of the body
  • Glandular: produces a secretion
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10
Q

What type of epithelium is endothelium? What is its function?

A
  • Simple squamous
  • It is found in the cardiovascular and lymphatic system, since its smooth internal structure allows flow of fluids. It’s thinness allows for easy exchange of substances.
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11
Q

What type of epithelium is mesothelium? What is it’s function?

A

-Simple squamous, with thicker layer of connective tissue than endothelium.
- It is a lubricated surface, and is located in our pleura, decreasing the friction between our lungs and rib cage.

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12
Q

Non-keratinized stratified squamous epithelium

A
  • Protective layer
  • Moist surface, lines mouth, oesophagus, nose, vagina etc.
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13
Q

Keratinized stratified squamous epithelium

A

Like non-keratinized stratified squamous epithelium, except with a layer of dead, anucleate cells in superficial layers. This surface is tough, and resistant to tearing.

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14
Q

Pseudostratified columnar ciliated epithelium with goblet cells

A
  • Nuclei on different levels, but all attached to basement membrane (hence psuedo-)
  • Goblet cells secrete mucus
  • Cilia filter pathogens and other shit upwards via a muco-cilliary escalator, where it can be swallowed or coughed out.
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15
Q

Transitional epithelium

A

Can change shape
- Stretched: stratified squamous
- Relaxed: stratified cuboidal
Location: ureters and bladder (makes sense; stretching is required)

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16
Q

How are glands formed?

A

Congregation and subsequent invagination of glandular epithelial cells. Connective support tissues will then grow around it.

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17
Q

What are the two destinations of exocrine gland secretion?

A
  • Into the lumen of an organ
  • Directly released onto epithelial cell (e.g. sweat)
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18
Q

What is the function of connective tissue? What properties allow it to do this?

A
  • Provide support and function to the body (tensile and strong)
  • Binds tissues and organs (flexible)
  • Facilitates communication (Forms a communication network)
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19
Q

What is the extracellular matrix of connective tissue made of?

A
  • Ground substance (viscous, fluid-like)
  • Fibres
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20
Q

What are the three types of fibres in the extracellular matrix of connective tissue?

A
  • Collagen
  • Elastic
  • Reticular
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21
Q

What is the main defining feature of connective tissue?

A

Extracellular matrix

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22
Q

What are the three classifications of connective tissue

A
  • Connective tissue proper
  • Fluid connective tissues
  • Supporting connective tissues
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23
Q

What different types of connective tissue structures enable it to provide mechanical support and protection?

A
  • Skeleton (structure and support)
  • Skin (support)
  • Fat (insulation, cushioning)
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24
Q

What are three other functions of connective tissue?

A
  • Energy storage
  • Immunity (carrying immune cells in blood)
  • Repair
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25
How does connective tissue provide a framework for communication?
Terconnected "highway" for messenger molecules, gases, nutrients, and waste.
26
What are the two types of connective tissue proper?
- Loose - Dense
27
What are the two types of fluid connective tissue?
- Blood - Lymph
28
What are the two types of supporting connective tissue?
- Cartilage - Bone
29
How is loose connective tissue defined?
Predominantly made of ground substance. Less fibres.
30
How is dense connective tissue defined?
Predominantly made of fibres, less ground substance.
31
What are the two classifications of dense connective tissue?
- Regular (parallel fibres) - Irregular (not parallel lines)
32
Function and location of dense regular connective tissue
Function: - Attach muscle to bone and bone to bone to allow for the transmission of force. Location: - Ligaments (B2B) and tendons (M2B)
33
Function and location of dense irregular connective tissue
Function: - Protect and encapsulate organs. Can absorb force from multiple directions. Location: - Dermis of skin - Capsules around organs
34
Function and location of loose connective tissue
Function: - Nourishment and cushioning - Allows passageway for blood vessels (and therefore immune defence) and nerves Location: - Underlying all epithilia - Sheaths muscles - Pleural and pericardal sacs
35
What is the function of ground substance
- Structural and biochemical support of cells - Regulates transport of substances (and therefore communication), including gases, waste and nutrients
36
True or false: ground substance is amorphous (no shape
True
37
How is ground substance secreted? What is the main component of ground substance?
Secreted mainly by fibroblasts. Mostly made of water.
38
Why does it matter that ground substance varies in viscosity?
- Determines how easily bacteria or other microbes can penetrate into the extracellular environment of the CT
39
How does swelling relate to connective tissue?
Swelling occurs due to abnormal accumulation of interstitial fluid in the ground substance of CT
40
How is elastin different from collagen? How do the effects of elastin change with time?
- Not as strong - Allows for coiling and recoiling, providing flexibility and elasticity - Elasticity diminishes with age
41
What structures do elastic fibres make up
- Skin - Arteries - Bronchi
42
How are reticular fibres different from collagen?
- Thinner and not as strong (inelastic like collagen) - Allow formation of flexible network/framework
43
What structures do reticular fibres support?
- Spleen - Liver
44
What are the three types of connective tissue cells?
- Structural and storage - Defense - Reserve
45
What are the types of structural and storage cells in connective tissue?
- Fibroblasts (secrete ground substance) - Fat cells
46
What are the types of defence cells in connective tissue?
- Marcophages - Leukocytes (migrating from blood) - Plasma cells
47
What are the reserve cells in connective tissue?
Stem cells
48
What is the most common cell in connective tissue?
Fibroblasts
49
Activity/function of fibroblasts
- Very metabolically active - Make fibres and ground substance - Respond to injury by dividing and secreting collagen (scar tissue)
50
Structure and function of adipocytes
- Source of energy (fat storage) - When aggregated, form shock absorbers (e.g. soles of feet, palms of hand) - White and brown fat
51
Where are leukocytes made?
- Bone marrow
52
What are some types of leukocytes?
- Neutrophils - Lymphocytes - Eosinophils
53
What is the role of plasma cell? How does this affect their rate of metabolic activity?
- Antibody secretion - Very metabolically active
54
What is the role of mast cells?
- Allergic reactions - Release histamine Culprits of hay fever
55
What happens when histamine is released?
- Vasodilation - Increased mucous production
56
Why is muscle tissue considered excitable?
It can propagate electrical signals. (also contractile)
57
What is another name for muscle cells?
Myocytes
58
What structures allow muscle fibres/cells to contract?
Microfilaments
59
How do muscle cells get their blood supply
Connective tissue between muscle fibres
60
What are the three main types of muscle?
- Skeletal - Cardiac - Smooth Muscle
61
Why are skeletal muscles multi-nucleated?
During development, multiple myoblasts come together to form fully differentiated myocytes, which therefore have multiple nuclei.
62
What are the shape of skeletal muscle cells?
Large and cylindrical (think of contraction)
63
What causes visible striations on myocytes?
Overlapping of microfilaments
64
Why do cardiac muscle cells look like one continuous cell?
They are long cells joined by intercalated discs
65
Is the nucleus of a cardiac muscle cell centralised or peripheral?
Centralised
66
Why does it make sense that cardiac muscle are connected by intercalated discs?
Contraction of the heart must be coordinated
67
Which type of muscle tissue has no striations?
Smooth muscle
68
What are the cytoplasmic extensions of a nerve cell?
- Dendrites - Axons
69
What are neuroglial cells?
Neural support cells (glia: latin -> glue)
70
What are the three key properties of neurons?
1. Excitability (detect stimuli) 2. Conductivity (generate propagate signal) 3. Secretory (release chemicals for intercellular communication)
71
Which three ways can neurons communicate with other cells?
- Neuron-neuron - Neuron-muscle - Neuron-gland