3.6 Blood Pressure & Flow Flashcards

1
Q

Which is longer: systole or diastole?

A

Diastole

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2
Q

Is aortic pressure higher during systole or diastole?

A

Systole

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3
Q

Is aortic pressure or ventricular pressure higher during diastole?

A

Aortic pressure. Decreases far less than ventricular pressure during diastole.

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4
Q

What two factors determine blood flow?

A
  • Pressure gradient along a vessel
  • Resistance to blood flow through a vessel
    (think: what is pushing it forward? what is pushing it back?)
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5
Q

Which physics equation can be used to describe the flow of blood through a vessel? Which values are substituted for which others?

A

Ohm’s Law (V=IR)
Voltage becomes pressure
Current becomes flow
Resistance is still resistance

Therefore, the two main factors that influence blood pressure are flow and resistance to flow.

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6
Q

What is the name given to the value that represents the difference between systolic and diastolic blood pressure?

A

Pulse pressure

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7
Q

Why isn’t MAP simply the average of systolic and diastolic pressure?

A

Diastole lasts slightly longer. Therefore, more weight must be given to diastole.

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8
Q

How does a pressure gradient influence the direction of blood flow?

A

Blood will flow from areas of high pressure to areas of low pressure (kind of like osmosis)

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9
Q

What is one factor that influences total peripheral resistance (think: tunica media)

A

Vasoconstriction/Vasodilation

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10
Q

What is meant by resistance and conductance? What is their relationship, and why does this matter?

A

Resistance: Impediment to blood flow in a vessel
Conductance: Measure of blood flow for a given pressure difference

These two quantities are reciprocals of one another, meaning they are inversely proportional.

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11
Q

What is the relationship between conductance and diameter of a vessel?

A

Conductance is proportional to the fourth power of diameter.

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12
Q

Why do tissues need blood flow?

A
  • Gas exchange (oxygen/CO2)
  • Nutrient delivery
  • H+ removal (pH conttrol)
  • Hormone transport
  • Thermoregulation
  • Tissue ion balance
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13
Q

Does the body have the ability to send the ideal amount of blood to all tissues in the body all the time?

A

No. It has to be selective. This is why, for example, many regions of the body do not get very much blood flow during exercise.

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14
Q

Name three factors that influence vascular resistance

A
  • Vessel Compliance
  • Length and diameter of vessel
  • Viscosity of blood
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15
Q

Why can’t you measure the flow of a capillary bed by measuring the flow of a single capillary?

A

At any given time, one capillary may be open, whilst the one next to it may be closed. This would not give a proper indication of the overall bed itself.

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16
Q

How does the body know which muscles are active and which are inactive?

A
  • Active tissues release vasodilatory substances (e.g. NO)
  • Endothelial derived factors respond to increase blood flow across vessel
  • Dampened sympathetic control
  • Muscle pump (think: Frank-Starling)
17
Q

What is vasomotion?

A

The flow of blood.

18
Q

Is blood flow through a capillary intermittent or continuous? How does this influence how we measure the blood flow through a capillary network?

A

Intermittent. Therefore, the blood flow throughout a capillary bed is averaged do determine vasomotion.

19
Q

What is the name given to the gap between two endothelial cells?

A

Intercellular cleft

20
Q

What are the two pairs of Starling forces?

A
  • Hydrostatic pressure (outward, caused by fluid) and interstitial fluid pressure (inward, caused by interstitial fluid)
  • Plasma colloid osmotic pressure and interstitial fluid colloid osmotic pressure
21
Q

Is blood flow usually uniform between tissues?

A
  • No
  • It is very specific depending on the requirements of any given tissue