8. Adrenergic Agonists and Antagonists I

Question 1

A 13 year old boy visits his PCP due to worsening asthma symptoms. He is regularly using his rescue inhaler once a day. The physician decides to prescribe a different medication that is better suited for long-term asthma control. Which adrenergic agonist did he likely prescribe? (MG)

A. Albuterol
B. Ipratropium
C. Salmeterol
D. Methanechol

Answer 1

C. Salmeterol

Only albuterol and salmeterol are adrenergic agonists of the options available. Albuterol is for acute attacks, salmeterol is for long-term management.

Question 2

Isoproterenol favors beta activation over alpha. When administered, it causes a decrease in MAP. This is due in part to a decrease in diastolic pressure mediated by which adrenergic receptor? (MG)

A. Alpha1
B. Alpha2
C. Beta1
D. Beta2
E. Beta3

Answer 2

D. Beta2

See increase in systolic pressure too, mediated by beta one

Question 3

Which of these is correct of the action of isoproterenol?

A. Bradycardia, Unchanged Systolic, Dropped Diastolic, Decreased Peripheral Resistance
B. Bradycardia, Increase Systolic , Dropped Diastolic, Increased Peripheral Resistance
C.Tachycardia, Decreased Systolic , Unchanged Diastolic, Decreased Peripheral Resistance
D. Tachycardia, Unchanged Systolic, Dropped Diastolic, Decreased Peripheral Resistance
E.Tachycardia, Increased Systolic, Increased Diastolic, Unchanged Peripheral Resistance

RFA

Answer 3

Ans. D. isoproterenol would

induce Tachycardia
While unchanging the Systolic pressure
Dropping Diastolic Pressure
Dropping peripheral resistance

Isoproterenol is used in emergencies to stimulate heart rate in patient with bradycardia or heart block

Question 4

A pregnant mother has developed hypertension during during which drug should she be treated with?

A. Phenylephrine 
B. Methyldopa
C. Pindolol 
D.Clonidine
E. Brimonidine 

RFA

Answer 4

Ans. B Methyldopa is the DOC for treatment of hypertension during pregnancy

A. Phenylephrine- is an A1 agonist it used for decongestion, it would increase BP

C. Pindolol- is a partial beta agonist and is the DOC for the women how HAVE HTN then get pregnant

D &E Clonidine and Bromondine- are both A2 agonist and would decrease BP they are used to treat migraines and glaucoma respectively

Question 5

Fenolopam is a dopamine agonist. It is used for HTN management via continuous IV bolus. Which of the following effects does it have?

A. Vasoconstriction
B. Vasodilation
C. Decrease MAP
D. Increase TPR
E. Increase MAP

SZ

Answer 5

Ans. B Vasodilation via D1 receptors

Question 6

Dobutamine is used during a stress echo because it acts as which of the following, causing this effect?

A. Beta 1 agonist, increase contractility
B. Beta 2 agonist, increase contractility
C. Alpha 1 agonist, decreasing HR
D. Alpha 2 agonist, increasing HR
E. Nonselective B agonist, increasing PVR

SZ

Answer 6

Ans. A. Beta 1 agonist, increase contractility