27. Thyroid Pathology

Question 1

A 42 year old woman come to the doctor complaints of a growth around her throat. Biopsy is taken notable for Psammoma bodies. What is the major risk factor associated with this condition?

A. Oral Contraceptive use
B. HLA associated Antibodies 
C Ionizing radiation 
D. Abnormality of binding protein 
E. Dietary iodine deficiency 

RFA

Answer 1

Ans. C the patient has Papillary carcinoma, hallmark is Psammoma bodies, ionizing radiation is the major risk factor

A. Oral Contraceptive use- is related to hyperprolactinemia

B. HLA associated Antibodies- are found in Type I DM and Hashimoto’s thyroiditis

D. Abnormality of bind protein- NTI

E. Dietary iodine deficiency- is related to Follicular carcinoma( well differentiated follicles that invade the capsules and spread into blood vessel)