42. Ovary Path II

Question 1

A 10 year old female presents to the clinic with abdominal pain, fever, and vaginal bleeding. She has a webbed necked, is in the 25th percentile for height, and her BP is 130/95 and has been consistently high her whole life. A mass is seen on imaging and biopsied to yield polyhedral tumor cells with round nuclei, clear cytoplasm, and adjacent inflammation. What types of cells will also be visible as infiltrate? (MG)

A. Macrophages
B. Neutrophils
C. Eosinophils
D. Lymphocytes
E. Plasma cells

Answer 1

D. Lymphocytes

Dx is dysgerminoma…. the girl has Turner syndrome which is a type of gonadal gysgenesis

Question 2

A 24yr old woman presents to the ED with complaints of lower abdominal pain for the past 3 days. Physical exam revealed TTP of the LLQ. On investigation a mass is seen on US in the LLQ. Biopsy of the mass is found to have remnants of all three germ layers. Which of the following tumors is the patient most likely to be diagnosed with? (MG)

A. Brenner tumor
B. Serous cystadenoma
C. Mature Teratoma
D. Follicular cyst
E. Mucinous cystadenoma

Answer 2

C. Mature Teratoma