7.2 Physiology of the Urinary System Part 2 Flashcards

1
Q

What is the pressure with which the filtrate enters the PCT?

A

net filtration pressure

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2
Q

What forces solutes and fluids out of the membrane of the glomerular capillary?

A

high hydrostatic blood pressure inside of the glomerular capillary

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3
Q

What cannot pass through the fenestrations of the glomerular capillary?

A

blood cells
blood proteins

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4
Q

What is the glomerular filtration rate?

A

amount of blood filtered by the glomerulus over time

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5
Q

What is the normal GFR?

A

120-125 ml/min or 180 L/day

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6
Q

What contributes to the GFR?

A

huge surface area
large degree of filtration membrane permeability
moderate net filtration pressure

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7
Q

What can increase the GFR?

A

increase in the arterial blood pressure in kidneys

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8
Q

What can decrease the GFR?

A

increase in glomerular osmotic pressure caused by dehydration

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9
Q

What are the three mechanisms that regulate renal flow and GFR?

A

renal autoregulation
nervous system control
hormone control

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10
Q

How if the GFR controlled under normal conditions?

A

kidney/renal autoregulation

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11
Q

What is renal autoregulation?

A

when the kidney determines its own rate of blood flow by controlling the diameter of the afferent or efferent arterioles

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12
Q

When is renal autoregulation superceded by the nervous system and hormone control?

A

during emergencies when blood flow needs to be diverted away from the kidney

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13
Q

What does the sympathetic nervous system do to GFR?

A

narrows the afferent arteriole diameter

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14
Q

What releases epinephrine?

A

adrenal medulla

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15
Q

What does epinephrine do to GFR?

A

decreases renal blood flow and decreases GFR by constricting renal arteries

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16
Q

What is the RAA system?

A

renin-angiotensin-aldosterone system

17
Q

When does the RAA system work?

A

when the body’s blood pressure drops too low

18
Q

What is angiotensinogen?

A

pre-enzyme produced by the liver and freely circulates in the blood

19
Q

When is renin released?

A

when blood pressure drops

20
Q

What releases renin?

A

juxtaglomerular cells of the nephron