Vasodilators & Tx of Angina

Question 1

Q

Answer 1

A

Question 2

Nitrate free intervals are needed due to

Answer 2

Tolerance

Question 3

MOA of nitrates

Answer 3

Relax vascular smooth muscle, at low doses dilate veins and at high doses dilate arterioles

Question 4

CCB are DOC for

Answer 4

Prinzmetal’s angina

Question 5

SE of nitrates

Answer 5

Postural hypotension, reflex tachycardia, hot flashes, and throbbing headache due to meningeal artery dilation

Question 6

Aspirin reduces mortality in unstable angina by

Answer 6

Platelet aggregation inhibition

Question 7

Nitrate used to prevent further attacks

Answer 7

Oral and transdermal forms of nitroglycerin

Question 8

Nitrate used for acute anginal attacks

Answer 8

Nitroglycerin sublingual tablets

Question 9

MOA of sildenafil (Viagra)

Answer 9

Inhibits phosphodiesterase-5, enhancing effects of nitric oxide-activated increases in cGMP

Question 10

Beta blockers are used for which type of anginal attack

Answer 10

Classic

Question 11

Drugs used in the management of angina

Answer 11

Aspirin, Nitrates, CCB, and Beta blockers