Local Anesthetics

Question 1

Almost all local anesthetics have this property and sometimes require the administration of vasoconstrictors (ex. Epinephrine) to prolong activity

Answer 1

Vasodilation

Question 2

Longer acting local anesthetics which are less dependent on vasoconstrictors

Answer 2

Tetracaine and bupivacaine

Question 3

LA causing methemoglobinemia

Answer 3

Prilocaine

Question 4

This may enhance activity of local anesthetics

Answer 4

Hyperkalemia

Question 5

This may antagonize activity of local anesthetics

Answer 5

Hypercalcemia

Question 6

These LA’s have surface activity

Answer 6

Cocaine and benzocaine

Question 7

Commonly abused LA which has cardiovascular toxicity including severe hypertension with cerebral hemorrhage, cardiac arrhythmias, and myocardial infarction

Answer 7

Cocaine

Question 8

Local anesthetic with vasoconstrictive property, favored for head, neck, and pharyngeal surgery

Answer 8

Cocaine

Question 9

Most important toxic effects of most local anesthetics

Answer 9

CNS toxicity

Question 10

MOA of local anesthetics (LA’s)

Answer 10

Block voltage-dependent sodium channels