Cholinoreceptor Blockers and Cholinesterase Regenerators Flashcards
Treatment of motion sickness
Scopolamine
Cystitis, postoperative bladder spasms, or incontinence
Oxybutynin, dicyclomine
Prototypical drug is atropine
Nonselective Muscarinic Antagonists
Bronchodilation in asthma and COPD
Ipratropium, tiotropium
Contraindications to use of atropine
Infants, closed angle glaucoma, prostatic hypertrophy
Atropine fever is the most dangerous effect and can be lethal in this population group
Infants
Reduce transient hyper GI motility
Dicyclomine, methscopolamine
Treat manifestations of Parkinson’s disease and EPS
Benztropine, trihexyphenidyl
Produce mydriasis and cycloplegia
Atropine and other anti-muscarinic agents
Toxicity of anticholinergics
Anti-DUMBBELSS
Another pneumonic for anticholinergic toxicity
“dry as a bone, red as a beet, mad as a hatter, hot as a hare, blind as a bat”