Drugs used in hemostasis

Question 1

Available bisphosphonates

Answer 1

Alendronate, etidronate, risedronate, pamidronate, tiludronate, and zoledronic acid

Question 2

Used intranasally and decreases bone resorption

Answer 2

Calcitonin (salmon prep)

Question 3

Used especially in postmenopausal women, dosage should be 1500 mg

Answer 3

Calcium

Question 4

Used for prevention of postmenopausal osteoporosis in women

Answer 4

Calcium reguators Bisphosphonates: alendronate, risedronate, ibandronate, Estrogen (HRT-Hormone replacement therapy)

Question 5

Major SE of bisphosphonates

Answer 5

Chemical esophagitis

Question 6

Bisphosphonates that cannot be used on continuous basis because it caused osteomalacia

Answer 6

Etidronate

Question 7

MOA of Bisphosphonates

Answer 7

Inhibits osteoclast bone resorption

Question 8

Uses of bisphosphonates

Answer 8

Osteoporosis, Paget’s disease, and osteolytic bone lesions, and hypercalcemia from malignancy

Question 9

Increase bone density, also being tested for breast CA tx.

Answer 9

Raloxifene (SERM-selective estrogen receptor modulator)

Question 10

Vitamin given with calcium to ensure proper absorption

Answer 10

Vitamin D