Adrenoreceptor Blockers

Question 1

Nonselective alpha-blocking drug, long acting and irreversible, and used to treat pheochromocytoma. Blocks 5-HT, so occasionaly used for carcinoid tumor. Blocks H1 and used in mastocytosis

Answer 1

Phenoxybenzamine

Question 2

Nonselective alpha-blocking drug, short acting and reversible, used for rebound HTN from rapid clonidine withdrawal, and Raynaud’s phenomena

Answer 2

Phentolamine

Question 3

Selective Alpha 1 blocker used for hypertension, BPH, may cause first dose orthostatic hypotension

Answer 3

Prazosin, terazosin, doxazosin

Question 4

Selective Alpha 2 blocker used for impotence (controversial effectiveness)

Answer 4

Yohimbine