Drugs of Abuse

Question 1

Q

Answer 1

A

Question 2

Removal of PCP may be aided

Answer 2

Urinary acidification and activated charcoal or continual nasogastric suction

Question 3

Causes acne, premature closure of epiphyses, masculinization in females, hepatic dysfunction, MI, and increases in libido and aggression

Answer 3

Steroids

Question 4

Sedative-Hypnotics action

Answer 4

Reduce inhibition, suppress anxiety, and produce relaxation

Question 5

Chronic high dose abuse of nicotine leads to

Answer 5

Psychotic state, overdose causes agitation, restlessness, tachycardia, hyperthermia, hyperreflexia, and seizures

Question 6

Most dangerous of the currently popular hallucinogenic drugs, OD leads to nystagmus, marked hypertension, and seizures, presence of both horizontal and vertical nystagmus is pathognomonic

Answer 6

PCP

Question 7

Treatments available for nicotine addiction

Answer 7

Patches, gum, nasal spray, psychotherapy, and bupropion

Question 8

Cause dizziness, tachycardia, hypotension, and flushing

Answer 8

Organic nitrites

Question 9

Inhalant anesthetics

Answer 9

NO, chloroform, and diethyl ether

Question 10

W/D from this drug causes anxiety and mental discomfort

Answer 10

Nicotine

Question 11

This agent may cause more severe, rapid and intense symptoms (abstinence syndrome) to a recovering addict

Answer 11

Naloxone

Question 12

Treatment for opioid addiction

Answer 12

Methadone, followed by slow dose reduction

Question 13

THC is active ingredient, SE’s include impairment of judgment, and reflexes, decreases in blood pressure and psychomotor performance occur

Answer 13

Marijuana

Question 14

Treatment of withdrawal syndrome involves

Answer 14

Long-acting sedative-hypnotic or a gradual reduction of dose, clonidine or propranolol

Question 15

This route is associated with rapid tolerance and psychologic dependence

Answer 15

IV administration

Question 16

Most commonly abused in health care professionals

Answer 16

Heroin, morphine, oxycodone, meperidine and fentanyl

Question 17

Toxic to the liver, kidney, lungs, bone marrow, peripheral nerves, and cause brain damage in animals, sudden death has occurred following inhalation

Answer 17

Fluorocarbons and Industrial solvents

Question 18

“Date rape drug”

Answer 18

Flunitrazepam (rohypnol)

Question 19

The most important sign of withdrawal syndrome

Answer 19

Excessive CNS stimulation (seizures)

Question 20

These agents are CNS depressants

Answer 20

Ethanol, Barbiturates, and Benzodiazepines

Question 21

These agents are congeners of Amphetamine

Answer 21

DOM, STP, MDA, and MDMA “ecstasy”

Question 22

Amphetamine agents

Answer 22

Dextroamphetamines and methamphetamine

Question 23

Common mechanism by which overdose result in death

Answer 23

Depression of medullary and cardiovascular centers

Question 24

Overdoses of this agent with powerful vasoconstrictive action may result in fatalities from arrhythmias, seizures, respiratory depression, or severe HTN (MI and stroke)

Answer 24

Cocaine “super-speed”

Question 25

Additive effects when Sedative-Hypnotics used in combination with these agents

Answer 25

CNS depressants

Question 26

Readily detected markers that may assist in diagnosis of the cause of a drug overdose include

Answer 26

Changes in heart rate, blood pressure, respiration, body temperature, sweating, bowel signs, and pupillary responses

Question 27

Withdrawal from this drug causes lethargy, irritability, and headache

Answer 27

Caffeine

Question 28

Tolerance is marked and abstinence syndrome occurs

Answer 28

Amphetamines

Question 29

Lacrimation, rhinorrhea, yawning, sweating, weakness, gooseflesh, nausea, and vomiting, tremor, muscle jerks, and hyperpnea are signs of this syndrome

Answer 29

Abstinence syndrome