Antidotes for DrugOD Flashcards

1
Q

Antidote used for carbon monoxide poisoning

A

100% O2 and hyperbaric O2

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2
Q

Method to reduce salicylate intoxication

A

Alkalinize urine, dialysis

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3
Q

Antidote for tissue plasminogen activator (t-PA), streptokinase

A

Aminocaproic acid

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4
Q

Antidote used for organophosphate/anticholinesterase poisoning

A

Atropine, pralidoxime (2-PAM)

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5
Q

Antidote used for iron salt toxicity

A

Deferoxamine

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6
Q

Antidote used for digitalis toxicity

A

Digibind (also need to d/c digoxin, normalize K+, and lidocaine if pt. Is arrhythmic)

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7
Q

Antidote for arsenic, mercury, and gold poisoning

A

Dimercaprol

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8
Q

Antidote for severe lead poisoning (with encephalopathy)

A

Dimercaprol AND CaEDTA (edetate calcium disodium)

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9
Q

Antidote used for lead poisoning (without encephalopathy)

A

Dimercaprol, Edetate calcium disodium, or succimer

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10
Q

Antidote used for beta agonist toxicity (eg. Metaproterenol)

A

Esmolol

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11
Q

Antidote used for methanol and ethylene glycol toxicity

A

Ethanol

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12
Q

Antidote used for benzodiazepine toxicity

A

Flumazenil

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13
Q

Antidote for beta-blocker overdose and hypoglycemia

A

Glucagon

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14
Q

Antidote for methotrexate toxicity

A

Leucovorin

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15
Q

Antidote useful for some drug induced Torsade de pointes

A

Magnesium sulfate

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16
Q

Antidote used for acetaminophen (APAP) toxicity

A

N-acetylcysteine

17
Q

Antidote used for opioid toxicity

A

Naloxone (IV), naltrexone (PO)

18
Q

Antidote used for cyanide poisoning

A

Nitrites, sodium thiosulfate, hydroxocobalamin (cyanokit)

19
Q

Antidote used in Wilson’s disease (copper poisoning)

A

Penicillamine

20
Q

Antidote used for anticholinergic poisoning

A

Physostigmine

21
Q

Antidote used for heparin toxicity

A

Protamine Sulfate

22
Q

Antidote used for tricyclic antidepressants (TCA)

A

Sodium bicarbonate

23
Q

Antidote for hyperkalemia

A

sodium polystyrene sulfonate (Kayexalate)

24
Q

Antidote used for warfarin toxicity

A

Vitamin K and Fresh frozen plasma (FFP)