Adrenocoritocsteroid and Adrenocorticol Antagonists

Question 1

Period of time of therapy after which GC therapy will need to be tapered

Answer 1

5-7 days

Question 2

Long acting GC’s

Answer 2

Betamethasone, dexamethasone, and paramethasone

Question 3

Short acting GC’s

Answer 3

Cortisone and hydrocortisone (equivalent to cortisol)

Question 4

Mineralocorticoids

Answer 4

Fludrocortisone and deoxycorticosterone

Question 5

Pneumonic for 3 zones of adrenal cortex

Answer 5

GFR

Question 6

3 zones of adrenal cortex and their products

Answer 6

Glomerulosa (mineralocorticoids), fasciculata (glucocorticoid=GC), and reticularis (adrenal androgens)

Question 7

Used for Addison’s disease, Congenital Adrenal Hyperplasia (CAH), inflammation, allergies, and asthma (as a local inhalation)

Answer 7

Glucocorticoids

Question 8

Some side effects of corticosteroids

Answer 8

Hyperglycemia, Osteopenia, impaired wound healing, inc. risk of infection, inc. appetite, HTN, edema, PUD, euphoria, psychosis

Question 9

Intermediate acting GC’s

Answer 9

Prednisone, methylprednisolone, prednisolone, oaramethasone, fluprednisone and triamcinolone