Antipsychotics Flashcards

1
Q

Q

A

A

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2
Q

Only phenothiazine not exerting antiemetic effects, can cause visual impairment due to retinal deposits, and high doses have been associated with ventricular arrhythmias

A

Thioridazine

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3
Q

Atypical antipsychotic causing high prolactin levels

A

Risperidone

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4
Q

Increased risk of developing cataracts

A

Quetiapine

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5
Q

Antipsychotics that reduce positive symptoms only

A

Older antipsychotics

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6
Q

Extrapyramidal dysfunction is more common with these agents, which block this subtype of dopamine receptor

A

Older antipsychotic agents, D2 receptors

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7
Q

Newer atypical antipsychotics that also improve some of the negative symptoms and help acute agitation

A

Olanzapine and aripiprazole

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8
Q

Newer atypical antipsychotic used for bipolar disorder, known to cause weight gain, and adversely affect diabetes

A

Olanzapine

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9
Q

Agents may exacerbate tardive dyskinesias (may be irreversible and there is no treatment)

A

Muscarinic blockers

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10
Q

Reduced seizure threshold

A

Low-potency typical antipsychotics and clozapine

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11
Q

Orthostatic hypotension and QT prolongation

A

Low potency and risperidone

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12
Q

Antipsychotic having the weakest autonomic effects

A

Haloperidol

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13
Q

Agent more frequently associated with extrapyramidal side effects that can be treated with benzodiazepine, diphenhydramine or muscarinic blocker

A

Haloperidol

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14
Q

Anti-psychotics available in depot preparation

A

Fluphenazine and haloperidol

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15
Q

Side effects occuring in antipsychotics that block dopamine

A

EPS, hyperprolactinemia, amennorrhea, galactorrhea, neuroleptic malignant syndrome

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16
Q

Drug used in neuroleptic malignant syndrome

A

Dantrolene

17
Q

Anti-psychotics shown not to cause tardive dyskinesia

A

Clozapine and quetiapine

18
Q

Agent with greater affinity to 5HT2A receptor; reserved for refractory schizophrenia, and can cause weight gain and agranulocytosis

A

Clozapine

19
Q

Antipsychotics having the strongest autonomic effects

A

Chlorpromazine or Thioridazine