Antipsychotics Flashcards
Q
A
Only phenothiazine not exerting antiemetic effects, can cause visual impairment due to retinal deposits, and high doses have been associated with ventricular arrhythmias
Thioridazine
Atypical antipsychotic causing high prolactin levels
Risperidone
Increased risk of developing cataracts
Quetiapine
Antipsychotics that reduce positive symptoms only
Older antipsychotics
Extrapyramidal dysfunction is more common with these agents, which block this subtype of dopamine receptor
Older antipsychotic agents, D2 receptors
Newer atypical antipsychotics that also improve some of the negative symptoms and help acute agitation
Olanzapine and aripiprazole
Newer atypical antipsychotic used for bipolar disorder, known to cause weight gain, and adversely affect diabetes
Olanzapine
Agents may exacerbate tardive dyskinesias (may be irreversible and there is no treatment)
Muscarinic blockers
Reduced seizure threshold
Low-potency typical antipsychotics and clozapine
Orthostatic hypotension and QT prolongation
Low potency and risperidone
Antipsychotic having the weakest autonomic effects
Haloperidol
Agent more frequently associated with extrapyramidal side effects that can be treated with benzodiazepine, diphenhydramine or muscarinic blocker
Haloperidol
Anti-psychotics available in depot preparation
Fluphenazine and haloperidol
Side effects occuring in antipsychotics that block dopamine
EPS, hyperprolactinemia, amennorrhea, galactorrhea, neuroleptic malignant syndrome