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Pharm One-Liners > Antihypertensives > Flashcards

Antihypertensives Flashcards

1
Q

A1a-selective blocker used for BPH

A

Tamsulosin (Flomax)

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2
Q

SE of clonidine

A

Rebound HTN, sedation, dry mouth

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3
Q

Non-selective Beta-blocker also used for migraine prophylaxis

A

Propranolol

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4
Q

ACE inhibitors are contraindicated in

A

pregnancy and with hyperkalemia

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5
Q

Alpha 1selective blockers

A

Prazosin, terazosin and doxazosin (-AZOSIN ending)

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6
Q

SE of methyldopa

A

Positive Comb’s test, depression

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7
Q

For rebound HTN from rapid clonidine withdrawal

A

Phentolamine

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8
Q

Non-selective Alpha1blockers use to treat pheochromocytoma

A

Phenoxybenzamine

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9
Q

SE of alpha blockers

A

Orthostatic hypotension (especially with first dose) and reflex tachycardia

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10
Q

IV Drug used Hypertensive Crisis

A

Nitroprusside

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11
Q

CCB with predominate effect on arteriole dilation

A

Nifedipine

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12
Q

Arterial vasodilator that works by opening K+ channels

A

Minoxidil

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13
Q

SE of hydralazine

A

Lupus-like syndrome

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14
Q

SE of minoxidil

A

Hypertrichosis

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15
Q

Direct vasodilator of arteriolar smooth muscle

A

Hydralazine

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16
Q

Methyldopa is contraindicated in

A

Geriatrics due to its CNS (depression) effects

17
Q

SE of ACE inhibitors

A

Dry cough, hyperkalemia

18
Q

Side effect associated with ACEI but not ARBs

A

Dry cough

19
Q

Toxicity caused by nitroprusside and treatment

A

Cyanide toxicity treated with sodium thiosulfate

20
Q

SE of CCB

A

Constipation, edema, and headache

21
Q

Presynaptic Alpha 2 agonist used in HTN

A

Clonidine, and methyldopa

22
Q

Block L-type calcium channel

A

Calcium channel blockers

23
Q

SE of beta blockers

A

Bradycardia, SEXUAL DYSFUNCTION, decrease in HDL, and increase in Triglycerols (TG)

24
Q

Reduce heart rate, contractility, and O2 demand

A

Beta-blockers

25
Q

Cardioselective Beta 1-blockers

A

Atenolol, acebutolol, and metoprolol

26
Q

Losartan and valsartan block

A

AT1 receptors

27
Q

Beta-blockers should be used cautiously in

A

Asthma (bronchospastic effects), diabetes (block signs of hypoglycemia) and peripheral vascular disease

28
Q

Nitroprusside vasodilates

A

Arteries and veins

29
Q

Inhibit angiotensin-converting enzyme (ACE)

A

ACE inhibitors

30
Q

Captopril and enalapril (-OPRIL ending) are

A

ACE inhibitors

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