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Pharm One-Liners > Drugs for Gout > Flashcards

Drugs for Gout Flashcards

1
Q

MOA of Colchicine (used in acute gout)

A

Selective inhibitor of microtubule assembly

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2
Q

Recombinant uricases that enhance uric acid metabolism

A

rasburicase, pegloticase

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3
Q

Agent used to treat chronic gout by increasing uric acid excretion through inhibition of URAT1 anion transporter

A

Probenecid

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4
Q

SE of colchicine

A

Kidney and liver toxicity, diarrhea, myelosuppression

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5
Q

NSAID used in gout

A

Indomethacin, ibuprofen

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6
Q

Agent that inhibits xanthine oxidases and used to treat chronic gout

A

Allopurinol, febuxostat

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7
Q

NSAID avoided in gout because low doses increases uric acid levels

A

Aspirin

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Pharm One-Liners (46 decks)

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