Drugs for Tx of Coag Disorders

Question 1

Q

Answer 1

A

Question 2

Vitamin K dependent anticoagulant

Answer 2

Warfarin (PT)

Question 3

Antidote to reverse actions of warfarin

Answer 3

Vitamin K or fresh frozen plasma

Question 4

Thrombolytic used for acute MI and ischemic (non hemorrhagic) CVA

Answer 4

Tissue plasmin activator

Question 5

Antiplatelet drug reserved for patients allergic to aspirin

Answer 5

Ticlopidine

Question 6

Thrombolytic that can cause allergic reaction

Answer 6

Streptokinase

Question 7

Thrombolytics are used for

Answer 7

Pulmonary embolism and DVT

Question 8

Antidote to reverse actions of heparin

Answer 8

Protamine sulfate

Question 9

Warfarin is contraindicated in

Answer 9

Pregnancy

Question 10

Route of administration of warfarin

Answer 10

Oral

Question 11

SE for ticlopidine

Answer 11

Neutropenia and agranulocytosis

Question 12

MOA of thrombolytics

Answer 12

Lyse thrombi by catalyzing the formation of plasmin which binds fibrin

Question 13

Alternative anticoagulant used if HIT develops

Answer 13

Lepirudin

Question 14

MOA of aspirin

Answer 14

Irreversibly blocks COX1 and COX2

Question 15

SE of heparin

Answer 15

Heparin induced thrombocytopenia (HIT)

Question 16

Anticoagulant of choice in pregnancy

Answer 16

Heparin

Question 17

SE of Aspirin

Answer 17

GI bleeding

Question 18

Prevents thrombosis in patients with artificial heart valve

Answer 18

Dipyridamole

Question 19

Effective in preventing TIA’s

Answer 19

Clopidogrel and ticlopidine

Question 20

SE of tPA

Answer 20

Cerebral hemorrhage

Question 21

SE of both warfarin and heparin

Answer 21

Bleeding

Question 22

Agent used to treat MI and to reduce incidence of subsequent MI

Answer 22

Aspirin

Question 23

Heparin (PTT) increases activity of

Answer 23

Antithrombin 3

Question 24

Antidote for thrombolytics

Answer 24

Aminocaproic acid

Question 25

Block glycoprotein IIb/IIIa involved in platelet cross-linking

Answer 25

Abciximab, tirofiban and eptifibatide

Question 26

Routes of administration of heparin

Answer 26

IV and subQ