Thyroid Disease Flashcards

1
Q

how much circulating T4 is protein bound?

A

99%

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2
Q

what is the common screening test for hypothyroidism in dogs?

A

total T4
very sensitive

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3
Q

what is the best screening test for cats with hypothyroid?

A

total T4
91% sensitivity

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4
Q

how does illness affect thyroid levels in dogs and cats?

A

total T4 levels will be decreased

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5
Q

how old are dogs with hypothyroidism usually?

A

middle-aged

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6
Q

which breeds are most at risk for hypothyroidism?

A

boxer
doberman pinscher
alaskan malamute

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7
Q

what does thyroid hormone do with erythropoiesis?

A

stimulates it

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8
Q

what are the clinical signs with hypothyroidism?

A

weight gain
cold intolerance
dermatologic problems
lethargy, mental dullness
weakness, exercise intolerance
reproductive problems

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9
Q

what laboratory abnormalities are seen with hypothyroidism?

A

mild non-regenerative anemia
increased platelet number, decreased size
hypercholesterolemia

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10
Q

how common are antithyroglobulin antibodies in dogs with hypothyroidism?

A

50%

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11
Q

what is levothyroxine?

A

oral or IV T4 supplementation

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12
Q

how do we monitor hypothyroid dogs on medication?

A

periodic measurement of serum total T4
peak level 4-6 hours post pill

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13
Q

who commonly has hyperthyroidism?

A

older cats- 13 years
no breed/sex predilection

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14
Q

what are some diagnostic findings with hyperthyroidism?

A

leukocytosis, slight increase in RBCs
elevated ALT
elevated phosphate
increased blood pressure

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15
Q

what is the safest and most effective form of therapy for hyperthyroid cats?

A

radioactive iodine

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16
Q

when should you be cautious with radioactive iodine?

A

cats already azotemic

17
Q

what should you monitor in a cat on methimazole?

A

total T4
CBC, platelets, liver enzymes
renal values, especially if already azotemic

18
Q

is hills y/d kidney friendly?

A

yes

19
Q

does developing azotemia with treatment of hyperthyroidism impact prognosis?

A

no, unless hypothyroid