Thyroid Disease Flashcards
how much circulating T4 is protein bound?
99%
what is the common screening test for hypothyroidism in dogs?
total T4
very sensitive
what is the best screening test for cats with hypothyroid?
total T4
91% sensitivity
how does illness affect thyroid levels in dogs and cats?
total T4 levels will be decreased
how old are dogs with hypothyroidism usually?
middle-aged
which breeds are most at risk for hypothyroidism?
boxer
doberman pinscher
alaskan malamute
what does thyroid hormone do with erythropoiesis?
stimulates it
what are the clinical signs with hypothyroidism?
weight gain
cold intolerance
dermatologic problems
lethargy, mental dullness
weakness, exercise intolerance
reproductive problems
what laboratory abnormalities are seen with hypothyroidism?
mild non-regenerative anemia
increased platelet number, decreased size
hypercholesterolemia
how common are antithyroglobulin antibodies in dogs with hypothyroidism?
50%
what is levothyroxine?
oral or IV T4 supplementation
how do we monitor hypothyroid dogs on medication?
periodic measurement of serum total T4
peak level 4-6 hours post pill
who commonly has hyperthyroidism?
older cats- 13 years
no breed/sex predilection
what are some diagnostic findings with hyperthyroidism?
leukocytosis, slight increase in RBCs
elevated ALT
elevated phosphate
increased blood pressure
what is the safest and most effective form of therapy for hyperthyroid cats?
radioactive iodine