The Icteric Cat and Dog Flashcards
where does heme come from?
red blood cells: hemoglobin, myoglobin, cytochrome
what percentage of septic cats have an increase in serum bilirubin?
63%
what infections can cause hemolytic anemia in cats?
mycocplasma
FeLV
what medications can cause hepatic icterus in cats?
oral diazepam
methimazole
what is the prevalence of lipid vacuoles in hepatic lipidosis?
> 50-60% of hepatocytes
what should you supplement in cats with idiopathic hepatic lipidosis?
glutathione
vitamin K
+/- vitamin B1
+/- carnitine
when is the prognosis of idiopathic feline hepatic lipidosis good?
if bilirubin decreases in first 5-7 days
what are the signs of acute neutrophilic cholangitis?
anorexia, lethargy, vomting
big three: fever, icterus, abdominal pain
what are the histologic patterns that cholantitis/cholecystitis can be?
acute neutrophilic cholangitis
chronic neutrophilic cholangitis
chronic lymphocytic cholangitis
what can lymphocytic cholangitis be hard to distinguish from?
small cell lymphoma
how can you treat lymphocytic cholangitis?
immunomodulation
hepatoprotectives
dietary: vitamin B12
what can cause post-hepatic icterus in a dog?
pancreatitis
gallbladder mucocele
cholelithiasis
cholecystitis
what is hyperbilirubinemia?
unusually large concentration of bilirubin in the blood
poor prognostic indicator in hepatobiliary and non-hepatobiliary disorders
how does sepsis cause cholestasis?
release of cytokines
down-regulation of hepatic transport proteins
is prehepatic icterus more common in dogs or cats?
dogs