Brain Tumors in Dogs and Cats Flashcards
are most brain tumors in dogs supratentorial or infratentorial?
supratentorial
what type of tumors is meningioma?
mesenchymal tumor
most often benign
where are most meningiomas in dogs?
olfactory bulb
frontal lobe and cortical
brainstem
what are the most common clinical signs of meningioma in dogs?
seizures
vestibular disease
what are the types of astrocytoma?
diffuse astrocytoma
anaplastic astrocytoma
glioblastoma multiforme
which dogs usually get choroid plexus tumors?
average age 6 years
mainly larger dogs, german shepherd dogs overrepresented
what are the goals of brain tumor treatment?
prolong lifespan, try to reach normal lifespan
strive for good quality of life
what is stereotactic radiation?
precisely-targeted radiation in fewer high-dose treatments than traditional therapy: helps to preserve healthy tissue
what is the median survival time with meningioma in dogs for palliative treatment?
2-4 months
what type of primary brain tumor is most common in dogs and cats?
meningioma
what type of secondary brain tumor is most common in dogs and cats?
dogs: hemangiosarcoma
cats: lymphoma
where are infratentorial tumors?
brainstem
cerebellum
24% of dog brain tumors
how many histologic subtypes of meningiomas are reported?
10
where are most meningiomas in cats?
cortical area
ventricular: lateral and 3rd
what is the signalment of a cat for meningioma?
DSH >80%
mean age 12
male to female 1.5:1
what is signalment of a dog for meningioma?
breeds: boxer, retriever
mean age 11
male=female
what are the most common clinical signs of meningioma in a cat?
altered mental status
circling
what are the categories of glioma?
astrocytoma
oligodendroglioma
what are the types of oligodendroglioma?
oligodendroglioma (WHO II)
anaplastic oligodendroglioma (WHO III)
where are choroid plexus tumors usually?
equal distribution lateral, third, fourth ventricles
what can be seen in CSF in a choroid plexus tumor?
elevated protein and WBC
carcinomas more pronounced CSF abnormalities than papilloma
are papillomas or carcinomas more common in choroid plexus tumors?
papillomas
what types of tumor is CT a good option for?
meningioma
can be used plexus papilloma
what makes a brain tumor biologically malignant?
location: most histological benign
what are the approaches for surgical resection?
transfrontal
rostrotentorial
caudal occipital
what are the complications with brain surgery?
aspiration pneumonia
emphysema subcutaneous
corneal ulceration
thromboembolism
hypernatremia
incisional dehiscence and/or infections
what is the mechanism of hydroxyurea?
interferes with DNA synthesis
S phase inhibitor
what cancer is hydroxyurea used for?
meningioma
what is the survival time for meningioma treated with radiation alone?
19 months
what is the percent recurrence for meningioma in cats treated with surgery?
21%
what is the survival time of gliomas like compared to meningiomas?
shorter
