Brain Tumors in Dogs and Cats

Question 1

are most brain tumors in dogs supratentorial or infratentorial?

Answer 1

supratentorial

Question 2

what type of tumors is meningioma?

Answer 2

mesenchymal tumor
most often benign

Question 3

where are most meningiomas in dogs?

Answer 3

olfactory bulb
frontal lobe and cortical
brainstem

Question 4

what are the most common clinical signs of meningioma in dogs?

Answer 4

seizures
vestibular disease

Question 5

what are the types of astrocytoma?

Answer 5

diffuse astrocytoma
anaplastic astrocytoma
glioblastoma multiforme

Question 6

which dogs usually get choroid plexus tumors?

Answer 6

average age 6 years
mainly larger dogs, german shepherd dogs overrepresented

Question 7

what are the goals of brain tumor treatment?

Answer 7

prolong lifespan, try to reach normal lifespan
strive for good quality of life

Question 8

what is stereotactic radiation?

Answer 8

precisely-targeted radiation in fewer high-dose treatments than traditional therapy: helps to preserve healthy tissue

Question 9

what is the median survival time with meningioma in dogs for palliative treatment?

Answer 9

2-4 months

Question 10

what type of primary brain tumor is most common in dogs and cats?

Answer 10

meningioma

Question 11

what type of secondary brain tumor is most common in dogs and cats?

Answer 11

dogs: hemangiosarcoma
cats: lymphoma

Question 12

where are infratentorial tumors?

Answer 12

brainstem
cerebellum
24% of dog brain tumors

Question 13

how many histologic subtypes of meningiomas are reported?

Answer 13

10

Question 14

where are most meningiomas in cats?

Answer 14

cortical area
ventricular: lateral and 3rd

Question 15

what is the signalment of a cat for meningioma?

Answer 15

DSH >80%
mean age 12
male to female 1.5:1

Question 16

what is signalment of a dog for meningioma?

Answer 16

breeds: boxer, retriever
mean age 11
male=female

Question 17

what are the most common clinical signs of meningioma in a cat?

Answer 17

altered mental status
circling

Question 18

what are the categories of glioma?

Answer 18

astrocytoma
oligodendroglioma

Question 19

what are the types of oligodendroglioma?

Answer 19

oligodendroglioma (WHO II)
anaplastic oligodendroglioma (WHO III)

Question 20

where are choroid plexus tumors usually?

Answer 20

equal distribution lateral, third, fourth ventricles

Question 21

what can be seen in CSF in a choroid plexus tumor?

Answer 21

elevated protein and WBC
carcinomas more pronounced CSF abnormalities than papilloma

Question 22

are papillomas or carcinomas more common in choroid plexus tumors?

Answer 22

papillomas

Question 23

what types of tumor is CT a good option for?

Answer 23

meningioma
can be used plexus papilloma

Question 24

what makes a brain tumor biologically malignant?

Answer 24

location: most histological benign

Question 25

what are the approaches for surgical resection?

Answer 25

transfrontal
rostrotentorial
caudal occipital

Question 26

what are the complications with brain surgery?

Answer 26

aspiration pneumonia
emphysema subcutaneous
corneal ulceration
thromboembolism
hypernatremia
incisional dehiscence and/or infections

Question 27

what is the mechanism of hydroxyurea?

Answer 27

interferes with DNA synthesis
S phase inhibitor

Question 28

what cancer is hydroxyurea used for?

Answer 28

meningioma

Question 29

what is the survival time for meningioma treated with radiation alone?

Answer 29

19 months

Question 30

what is the percent recurrence for meningioma in cats treated with surgery?

Answer 30

21%

Question 31

what is the survival time of gliomas like compared to meningiomas?

Answer 31

shorter