Atlanto-Axial Luxation and Syringohydromyelia Flashcards

1
Q

where is the axial ligament?

A

dorsal arches of atlas and axis

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2
Q

what does the apical ligament do?

A

connects dens to occipital condyles

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3
Q

what are some congenital malformations for atlanto-axial luxation?

A

aplasia of dens
hypoplasia of dens
absence of ligaments

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4
Q

which breeds usually have atlanto-axial luxation?

A

toy poodle
chihuahua
yorkshire terrier
pomeranian
shih tzu
dachshund

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5
Q

what should you not do when taking radiographs of an atlanto-axial luxation?

A

do not flex the neck

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6
Q

what is the prognosis of atlanto-axial luxation with medical treatment?

A

50% do well

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7
Q

what is done in surgical treatment of atlanto-axial luxation?

A

definitive re-alignment and decompression
ventral fusion and permanent biological fixation

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8
Q

what are the difficulties with surgical treatment of atlanto-axial luxation?

A

small dogs: difficult screw placement
young dogs: soft and immature bone
damage of large blood vessels
spinal cord trauma

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9
Q

what are the long term complications of atlanto-axial luxation?

A

implant failure
infection
dysphagia

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10
Q

what primary spinal cord disorder can cause syringohydromyelia?

A

spinal arachnoid cysts

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11
Q

what primary brain disorders can cause syringohydromyelia?

A

brain tumors
CSF overproduction by plexus papilloma
dermoid or epidermoid cyst

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12
Q

what are the diagnostic MRI findings with chiari-like malformation?

A

rostral displacement of cerebellum
cerebellar coning
kinked medulla
syringohydromeylia
ventricular enlargement
attenuation of subarachnoid space at cervico-medullary junction

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13
Q

where does CSF flow normally during diastole?

A

rostral

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14
Q

which breed is especially predisposed to chiari-like malformation?

A

cavalier king charles spaniel: autosomal recessive trait, incomplete penetrance

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15
Q

what correlates best with clinical signs in chiari-like malformation and syringohydromyelia?

A

maximal diameter of syrinx

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16
Q

what does the transverse ligament of the atlas do?

A

holds dens against ventral arch of atlas

17
Q

what do the paired alar ligaments do?

A

connect dens to ventral foramen magnum and occipital condyles

18
Q

what trauma can lead to atlanto-axial luxation?

A

dens fracture

19
Q

what is atlanto-axial luxation often triggered by?

A

minor trauma

20
Q

when is the common onset of clinical signs with atlanto-axial luxation?

A

<12 months 70%
<24 months 80%

21
Q

what are clinical signs with atlanto-axial luxation?

A

wide range
pain
ataxia
tetraparesis
tetraplegia
respiratory compromise

22
Q

what is medical management like with atlanto-axial luxation?

A

not re-aligning C1 and C2
just avoid movement and spinal cord compression
secondary fibrosis might help to stabilize

23
Q

what is done surgically for atlanto-axial luxation?

A

definitive re-alignment and decompression
ventral fusion and permanent biological fixation

24
Q

what are some complications immediately post surgery for atlanto-axial luxation?

A

death
implant causing spinal cord trauma
laryngeal paralysis
hypoventilation due to spinal cord trauma
worsening neurological condition
aspiration pneumonia

25
what are some predictive factors for good outcome after surgery with atlanto-axial luxation?
mild neurological signs young dog short duration of clinical signs bigger dog
26
what is the difference between hydromyelia and syrinx?
hydro: central canal and has epithelial lining syrinx: cavity, no epithelium
27
what are the general causes of syringohydromyelia?
primary spinal cord disorders primary brain disorders chiari-like malformation
28
what is increased in chiari-like malformation?
cerebellar volume CSF flow at foramen magnum fibrous hypertrophy of meninges
29
what leads to syrinx formation with chiari-like malformation?
cyclic pressure wave into spinal cord accumulation due to valve effect at foramen magnum abnormal drainage of CSF from spinal cord into 4th ventricle unequal spatial vascular pressure above and below stenosis causes nervous tissue damage
30
what is the age at onset of chiari-like malformation?
11 months- 13 years mainly young
31
what brainstem signs can be seen with chiari-like malformation?
head tilt facial nerve paralysis tongue weakness dysphagia
32
what can you use to lower CSF production in chiari-like malformation?
omeprazole acetazolamide