Diabetes Mellitus and Diabetic Ketoacidosis Part II

Question 1

what are SGLTs?

Answer 1

family of proteins important in glucose absorption from the kidney and intestine

Question 2

what are the advantages of sodium glucose cotransporter inhibitors?

Answer 2

minimal risk of hypoglycemia
once daily, oral administration- palatable
boarding, pet sitting
ease of instituting weight loss program

Question 3

what is the most serious side effect of SGLT2 inhibitor?

Answer 3

DKA

Question 4

what is diabetic ketoacidosis characterized by?

Answer 4

relative or absolute insulin deficiency and glucagon excess with or without elevations in counterregulatory hormones

Question 5

what is the clinical presentation of diabetic ketoacidosis?

Answer 5

vomiting
weakness, lethargy, depression
abnormal respiration
dehydration, tachycardia, abdominal pain
hypothermia, hyperthermia

Question 6

how is diabetic ketoacidosis diagnosed?

Answer 6

hyperglycemia
euglycemia
ketonuria or ketonemia
high anion gap metabolic acidosis