Respiratory system linking symptoms and physiology Flashcards

1
Q

Static lung measurement

A
  • Measures capacity and volume
  • Information about restrictive lung diseases - lung cancer
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2
Q

Dynamic measurement

A
  • How quickly air can be moved out or into the lung
  • Asthma and COPD
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3
Q

Symptoms of Asthma

A
  • Shortness of breath
  • Wheezing when exhaling - recoil difficult
  • Tightness of chest
  • Chronic cough
  • Variable breathing
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4
Q

Asthma

A
  • Chronic inflammatory disorder of airways (could be genetic)
  • Reversible airway obstruction to increase airway response
  • Airway obstruction
  • Bronchospasm
  • Airway remodelling
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5
Q

What causes asthma

A
  • House dust mite
  • Pets
  • Fungal spores
  • Smoking
  • Pollution
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6
Q

Asthma on peak flow meter

A
  • Peak flow drops early
  • Also late phase response
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7
Q

Lumen of the artery of Asthma patient

A
  • Increased smooth muscle growth
  • Bronchoconstriction smooth muscle contraction during an asthma attack
  • Airways are narrower
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8
Q

Blocking of lumen alveoli

A
  • Mucus formation in addition to bronchoconstriction less oxyen reaching bloodstream
  • Must work harder to overcome increased resistance
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9
Q

Nor-adrenaline effect on muscles

A
  • Relaxes the airway by dialating the smooth muscle - Adrenergic receptor beta 2
  • Agonist such as Salbutamol
  • Small activity on Beta 1 receptors
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10
Q

Mechanism of Salbutamol

A
  • Salbutamol binds to the receptor releasing the alpha and GTP to bind to adeynyl cyclase
  • Second messenger for protien kinase to relax the lungs
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11
Q

Inhaler types

A
  • Preventer inhaler and reliever inhaler
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12
Q

Meter-dose inhaler

A
  • Device make aerosol
  • Breath slowly and deeply
  • Use a spacer device
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13
Q

Dry powder inhaler

A
  • Breathing hard and fast suck power into the mouth
  • Cannot use spacer
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14
Q

Good inhaler technique

A
  • 20% into the lung 80% in the gut
  • Causes heart tremmors through the gut side effects
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15
Q

Peak expiration flow

A
  • Measure how quickly you can blow air out of the lungs
  • Seal mouth put meter to zero
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16
Q

Diagnosis

A
  • Less than 20% of normal means that slighly concered
  • 20% to 50% action plan required