Regulation of gene expression Flashcards
1
Q
Reason for gene expression
A
- More efficient to turn on the gene only when required conserve energy and space
2
Q
Procees of gene expression
A
1) What cell?
2) Which chromasome?
3) What part of DNA?
4) What protien?
5) How much?
6) How long?
7) Where is it going?
3
Q
Epigenetics
A
- Heritable changes that do not involve chages in DNA sequence
- Via histones DNA tightly wound around
4
Q
Gene expression
A
- Process that controls the turning on and off of a gene
5
Q
Post-transcriptional
A
- Control of gene expression after the RNA molecule has been created but before translation
6
Q
Acetylation
A
Decrease in attraction DNA unwind open acess and gene expression
7
Q
De-aceytlation
A
Locked and repressed removal of acetyl
8
Q
Methylation
A
- Decreased attraction unwind so DNA polymerase can acess gene
- 2+ methyl groups on histones no expression
9
Q
Promotor region
A
- Transcription factor stimulates the promotor region to intiate DNA helicase for transcription
10
Q
Enhancer/repressor
A
- Transcription factor comes in to contact with Enhacer
- Has an activator binds to the transcription factor to form a complex
- Stimulates histone acetylation
11
Q
Repressor
A
- Silecncer binds to the repressor to prevent transcription from occouring
12
Q
Sliceasomes
A
- Splice the introns to form mature mRNA from Pre-mRNA
13
Q
Formation of mRNA
A
- Addition of 7 methyl guanine on 5’ and polyatail on 3’
- Prevents exonuclease from digesting the exon
14
Q
RNA editing
A
- Adenosine to Inosine
- Cyrosine to Uracil
