Plasma membrane: Composition & Functions Flashcards

1
Q

Plasma membrane

A
  • Boundary separates living cells from surround
  • Barrier to prevent contents of the cell from escaping nutrient in waste out (selective permeable)
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2
Q

Fluid mosaic model

A
  • Dynamic and complex structure of plasma membrane that contains glycolipids, sterols, proteins and glycoproteins embedded
  • Lipid molecules 2d move along the plane of the bilayer (fluidity dependant on composition of bilayer)
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3
Q

Movement of Phospholipid membrane

A
  • Rapid lateral movement
  • Spin in its place
  • Flexion contract movement
  • Flip flop side to side
  • Protein anchored by cytoskeleton
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4
Q

Cholesterol

A
  • Only in animal cell
  • Modulates stability & improves it
  • Stiffen membrane less soluble & fluid reduce molecule passage
  • Glycolipids sugar group always facing exterior
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5
Q

Membrane protiens

A
  • Synthesised in rough ER
  • Mostly transmembrane proteins
  • Hydrophobic region has coiled alpha helices interior
  • Other proteins are embedded in the membrane exclusively
  • Peripheral proteins either side of membrane covalently attached to membranes lipids
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6
Q

Function of membrane proteins

A
  • Transport of molecules
  • Enzyme activity
  • Cell communication
  • Support and attachment of extracellular membrane
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7
Q

Definition

Passive transport

A
  • Selectively permeable
  • Without expenditure of energy
  • Move down concentration gradient
  • High to low conc until equilibrium is reached
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8
Q

Diffusion

A
  • Free movement of particles across lipid bilayer (net)
  • No energy required down concentration gradient
  • Uncharged polar molecules and CO2 and O2 urea & ethanol
  • Organic molecule too large to diffuse
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9
Q

Osmosis

A
  • Spontaneous passive transport of water across a semipermeable membrane high to low water potential
  • Water potential inverse to solute conc
  • Hydrostatic pressure required to stop net flow of water across membrane water flow in and out via aquaporins
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10
Q

Isotonic

A

Same concentration of solute in and out of cell (normal cell)

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11
Q

Hypertonic

A

Solution higher solute conc outside cell compare to inside (shrivel cell)

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12
Q

Hypotonic

A

higher solute con inside than outside cell (burst cell)

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13
Q

Facillitated diffusion

A
  • Passive movement down conc grad via transport proteins
  • Channel protein and protein carrier
  • Highly specific and no energy require
  • Reversible
  • Specific ions hydrophilic glucose
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14
Q

Uniport

A
  • Shift and transport a single type of molecule
  • Specific confirmational change protein when entering channel
  • Slower rate than other channels
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15
Q

Symports

A

Moves 2 different molecules across the cell in the same direction

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16
Q

Antiporters

A

Move 2 distinct proteins opposing directions Na+ and K+ pump 3 in and 2 out

17
Q

Active transport

A
  • Moves substance against concentration gradient
  • Energy ATP required
  • Specific protein embedded in membrane enabling stockpiling
  • Specific bind site can be saturated and inhibited and catalysed
18
Q

Endocytosis

A
  • Uptake of macromolecules
  • Form intracellular membrane-bound vesicle containing extracellular fluid
19
Q

Exocytosis

A
  • Secretion and excretion insulin by pancreatic cell
    Transport molecules migrate to plasma membrane fuse release content