Cardiovascular System - Cardiac cycle, sounds and rhythms Flashcards

1
Q

Systole

A
  • Heart contaction
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2
Q

Diastole

A

Relaxation of heart

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3
Q

Atria contraction

A
  • Diastole initial when the atrium is filling with blood
  • then Atrium in systole when contracting and pushing blood to ventricle
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4
Q

Ventrical contraction

A
  • Initially diastole when the ventricle is being filled with blood from atrium
  • Systole when ventricle contracts until all blood enters either aorta or pulmonary vein then returns to diastole
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5
Q

Sino Atrial node

A
  • Specialised electrically active Myocardial tissue of atrium
  • Intrinsic unstable spontaneous depolarisation
  • Generates electrical activity-Impulse
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6
Q

Atria ventricular node

A
  • Specialised electrically active Myocardial tissue ventricular midline
  • Intrinsic unstable spontaneous depolarisation
  • Generates electrical activity-Impulse
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7
Q

Inter nodal tracks

A
  • Conduction pathways (Anterior, Middle & Posterior)
  • Carry pulse, depolarise and contract atria (right and left)
  • Converge at AV node
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8
Q

Fibrous mid-line

A

No electical conductivity

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9
Q

Bundle of HIS (AV bundle)

A
  • Collect and carry to higher and lower part of the ventricles
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10
Q

Purkinge Fibres

A

Specialised myocardium for electrical conduction towards contractile myocytes

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11
Q

Vagus innervation

A

Suppress the heart rate

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12
Q

Sympathetic Innervention

A

-Stimulates the AV and SA node this increases the heart rate

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13
Q

Cardiac muscle

A
  • Striated branched muscle fibre containing single nucleus with many mitochondria
  • Gap junctions so depolarisation between cells
  • Desmosomes hold the fibres close together in contractions
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14
Q

Properties of Cardiac muscle

Auto-rhythmicity

A

Ability to initiate heart rate consistent and continuous at regular pace without any external stimuli (autonomic)

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15
Q

Properties of Cardiac muscle

Excitability

A
  • Ability to respond to stimuli of adequate strength and duration (threshold or more)
  • Ability to generate and process action potential
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16
Q

Properties of Cardiac muscle

Conductivity

A

Ability to conduct and transmit impulse through the cardiac tissue

17
Q

Properties of Cardiac muscle

Contractility

A

Ability to contract in response to stimulation (mechanical)

18
Q

Exitation-Contraction Coupling in Contractile Myocytes

Step 1 - Action Potential arrival

A

Action Potential from adjacent cell excites myocytes and trigger membrane depolarisation in T-tubules

19
Q

Exitation-Contraction Coupling in Contractile Myocytes

Step 2 - Calcium enters cell

A

Calcium enters the cell via voltage gated channel open the calcium enters cell

20
Q

Exitation-Contraction Coupling in Contractile Myocytes

Step 3 - Calcium binding

A

Calcium binds to Ryanodine receptor (RYR) and induce Calcium release from SR

21
Q

Exitation-Contraction Coupling in Contractile Myocytes

Step 4 - Trigger myosin

A

Calcium binds to troponin and triggers acting-myosin complex and contraction

22
Q

Exitation-Contraction Coupling in Contractile Myocytes

Step 5 - Calcium unbind

A

Calcium unbind from troponin and pumped back into SR

23
Q

Exitation-Contraction Coupling in Contractile Myocytes

Step 6 - Calcium causing relaxing

A

Calcium unbinding cause relaxation and excess Ca2+ exchanged with Na+

24
Q

Exitation-Contraction Coupling in Contractile Myocytes

Step 7 - Maintainance of Na+ gradient

A

Na+ gradient is maintained by sodium-potassium- ATPase pump.

25
Q

P wave

A

Atria depolarlisation contraction (systole)

26
Q

QRS complex

A
  • Isovolumetric contraction when ventricle is filling
  • Ventricle depolarisation
27
Q

T wave

A

Ventricle repolarisation

28
Q

Atrial Systole

A
  • Atrial myocardium contraction for 0.1 sec
29
Q

Ventricle Systole

A

Ventricular myocardium contraction at 0.3s

30
Q

Synus Rhythums

A
  • Calculate by observing the R-R intervals
  • Calculate if there is Sinus bradycardia less beats per minute
  • Sinus tachycardia heart beat too fast
31
Q

ECG readings

A

1mV = 10mm high
5 boxes across is 1s

32
Q

Sinus bradycardia

A
  • Rate is less than 60bpm
  • Usually asymptomatic beta blockers and calcium channel blockers my be the cause
33
Q

Sinus tachycardia

A
  • rate greater than 100bpm
  • Occours in exercise and stress
  • Asymptomatic could by hypervolemea