Renal 4 Flashcards
clearance
the rate at which solute disappears from the body by excretion or metabolism
Clearance of X =
excretion rate of X / [X]plasma
Clinicians commonly use __________ clearance as a measure of GFR and indicator of renal function
creatinine
creatinine clearance slightly ____________ GFR
overestimates
inulin clearance is ______ to GFR
equal
net reabsorption
If clearance of a substance is less than what was filtered
net secretion
If clearance of a substance is greater than what was filtered
GFR=clearance
filtered, not reabsorbed, not secreted
micturition reflex
filling of the bladder activating stretch receptors
Urge to urinate appears around..
200ml
____ left in bladder after micturition
~10ml
When are internal sphincters forced open?
once exceeding 500ml
incontinence
inability to control urination voluntarily
Causes of incontinence
infancy, damage to internal or external sphincter, spinal cord damage, aging