Lecture 3 Flashcards

1
Q

body fluid compartments

A

ICF and ECF

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2
Q

ICF

A

2/3 of total body water volume

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3
Q

ECF

A

1/3 of total and consists of interstitial fluid and blood plasma

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4
Q

interstitial fluid

A

lies between circulatory system and cells

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5
Q

blood plasma

A

liquid matrix of blood

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6
Q

ECF and ICF are in…

A

osmotic equilibrium

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7
Q

osmosis

A

movement of water across a membrane in response to a solute conc. gradient

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8
Q

water can move freely between…

A

ICF and ECF through aquaporin channels

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9
Q

how many different aquaporin channels?

A

13

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10
Q

osmotic equilibrium does not equal…

A

chemical or electrical equilibrium

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11
Q

osmolarity

A

describes the number of particles in solution (osmol/L)

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12
Q

osmotic movement of water can be predicted by knowing…

A

the concentrations of each solution

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13
Q

normal osmolarity in the human body is….

A

280-296 mOsm

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14
Q

isosmotic

A

solutions have identical osmolarities

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15
Q

hypersmotic

A

describes the solution with the higher osmolarity

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16
Q

hyposmotic

A

describes the solution with the lower osmolarity

17
Q

tonicity

A

describes a solution and how it would affect cell volume if a cell were placed in the solution and allowed to come to equilibrium

18
Q

water moves in higher penetrating or non-penetrating?

A

non-penetrating

19
Q

simple diffusion

A

the movement of molecules from an area of high conc. to low conc.

20
Q

Diffusion uses…. energy and not…..

A

kinetic, outside energy

21
Q

diffusion continues until….

A

conc. come to equil.

22
Q

diffusion is faster…

A
  • along higher conc. gradients
  • over short distances
  • at higher temp.
  • for smaller molecules
23
Q

rate of diffusion through a membrane is faster if…

A
  • larger membrane surface area
  • thin membrane
  • large conc. gradient
  • membrane is more permeable to molecule
24
Q

membrane permeability depends on…

A
  • molecule’s lipid solubility
  • molecule size
  • lipid composition
25
Q

Law of Diffusion

A

Fick

26
Q

channel proteins

A

made of membrane spanning protein subunits with a pore through the center; FAST

27
Q

how are channel proteins names?

A

according to substances that pass through

28
Q

open channels =

A

leak channels

29
Q

different kinds of gated channels

A

chemically, voltage, and mechanically

30
Q

carrier proteins

A

large complex proteins that slowly transport substance that cannot pass through channels by changing conformation