Muscles 1 Flashcards

1
Q

In all muscle types, the generation of force depends on…

A

the conversion of chemical energy (ATP)

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2
Q

Three kinds of muscle

A

skeletal, cardiac, smooth

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3
Q

skeletal muscles

A
  • primarily voluntary

- multinucleated

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4
Q

cardiac muscles

A
  • primarily involuntary

- uninucleated

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5
Q

smooth muscle

A
  • primarily involuntary

- uninucleated

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6
Q

Which muscle type has no striations?

A

smooth

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7
Q

skeletal muscles attach to bones by…

A

tendons

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8
Q

origin

A

closest to trunk or to more stationary bone

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9
Q

insertion

A

more distal or more mobile attachment

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10
Q

flexor

A

brings bones together

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11
Q

extensor

A

moves bones away

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12
Q

40% of total body weight…

A

skeletal muscle

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13
Q

muscle cell=

A

muscle fiber

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14
Q

cell membrane=

A

sarcolemma

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15
Q

cytoplasm=

A

sarcoplasm

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16
Q

modified endoplasmic reticulum=

A

sarcoplasmic reticulum

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17
Q

muscle fascicle

A

bundle of muscle fibers

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18
Q

muscle fibers

A

bundle of myofibrils

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19
Q

striations

A

correspond to ordered arrays of thick and thin filaments within myofibrils

20
Q

one sarcomere

A

from a z-disk to another z-disk

21
Q

thin filaments

A

f-actin, tropomyosin, troponin complex

22
Q

f-actin

A

double stranded alpha helical polymer of G-actin molecules; contains binding site for thick filaments

23
Q

tropomyosin

A

two identical alpha helices the coil and sit around actin strands; regulate binding of myosin to actin

24
Q

troponin complex

A

TnT, TnC, TnI; situated approx. every 7 actin molecules

25
Q

troponin T

A

binds to a single molecule of tropomyosin

26
Q

troponin C

A

Calcium binding site

27
Q

troponin I

A

under resting conditions is bound to actin, inhibiting contraction

28
Q

thick filaments

A

consists of a bundle of myosin molecules

29
Q

myosin

A

two intertwined heavy chains

30
Q

heavy chains

A

contains two light chains

31
Q

regulatory lights chain

A

regulates ATPase activity of myosin

32
Q

essential light chain

A

stabilizes myosin head

33
Q

Myosin head contains…

A

region for binding actin and a site for binding and hydrolyzing ATP (ATPase)

34
Q

titin

A

a protein intending from M line to Z line; involved in stabilization and elastic recoil of muscle

35
Q

nebulin

A

a protein that wraps around the thin filament; regulate length of thin filaments and contribute to structural integrity of myofibrils

36
Q

Z disk

A

attachment site for thin filaments

37
Q

I bands

A

lightest band of sarcomere; region occupied only by thin filaments

38
Q

A band

A

darkest band of sarcomere; encompasses entire length of thick filaments and area where thin and thick overlap

39
Q

H zone

A

central region of A band with only thick filaments

40
Q

M line

A

attachment site for thick filaments

41
Q

glucose within the sarcoplasm

A

stored as glycogen

42
Q

sliding filament model

A

muscle contraction - H zone and I band shorten

43
Q

tension

A

force generated by a contracting skeletal muscle

44
Q

neuromuscular junction

A

point of synaptic contact between somatic motor neuron and individual muscle fibre

45
Q

excitation-contraction coupling

A

an action potential initiated in skeletal muscle fibre resulting in an increase in intracellular Ca2+