Muscles 1 Flashcards

1
Q

In all muscle types, the generation of force depends on…

A

the conversion of chemical energy (ATP)

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2
Q

Three kinds of muscle

A

skeletal, cardiac, smooth

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3
Q

skeletal muscles

A
  • primarily voluntary

- multinucleated

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4
Q

cardiac muscles

A
  • primarily involuntary

- uninucleated

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5
Q

smooth muscle

A
  • primarily involuntary

- uninucleated

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6
Q

Which muscle type has no striations?

A

smooth

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7
Q

skeletal muscles attach to bones by…

A

tendons

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8
Q

origin

A

closest to trunk or to more stationary bone

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9
Q

insertion

A

more distal or more mobile attachment

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10
Q

flexor

A

brings bones together

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11
Q

extensor

A

moves bones away

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12
Q

40% of total body weight…

A

skeletal muscle

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13
Q

muscle cell=

A

muscle fiber

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14
Q

cell membrane=

A

sarcolemma

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15
Q

cytoplasm=

A

sarcoplasm

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16
Q

modified endoplasmic reticulum=

A

sarcoplasmic reticulum

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17
Q

muscle fascicle

A

bundle of muscle fibers

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18
Q

muscle fibers

A

bundle of myofibrils

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19
Q

striations

A

correspond to ordered arrays of thick and thin filaments within myofibrils

20
Q

one sarcomere

A

from a z-disk to another z-disk

21
Q

thin filaments

A

f-actin, tropomyosin, troponin complex

22
Q

f-actin

A

double stranded alpha helical polymer of G-actin molecules; contains binding site for thick filaments

23
Q

tropomyosin

A

two identical alpha helices the coil and sit around actin strands; regulate binding of myosin to actin

24
Q

troponin complex

A

TnT, TnC, TnI; situated approx. every 7 actin molecules

25
troponin T
binds to a single molecule of tropomyosin
26
troponin C
Calcium binding site
27
troponin I
under resting conditions is bound to actin, inhibiting contraction
28
thick filaments
consists of a bundle of myosin molecules
29
myosin
two intertwined heavy chains
30
heavy chains
contains two light chains
31
regulatory lights chain
regulates ATPase activity of myosin
32
essential light chain
stabilizes myosin head
33
Myosin head contains...
region for binding actin and a site for binding and hydrolyzing ATP (ATPase)
34
titin
a protein intending from M line to Z line; involved in stabilization and elastic recoil of muscle
35
nebulin
a protein that wraps around the thin filament; regulate length of thin filaments and contribute to structural integrity of myofibrils
36
Z disk
attachment site for thin filaments
37
I bands
lightest band of sarcomere; region occupied only by thin filaments
38
A band
darkest band of sarcomere; encompasses entire length of thick filaments and area where thin and thick overlap
39
H zone
central region of A band with only thick filaments
40
M line
attachment site for thick filaments
41
glucose within the sarcoplasm
stored as glycogen
42
sliding filament model
muscle contraction - H zone and I band shorten
43
tension
force generated by a contracting skeletal muscle
44
neuromuscular junction
point of synaptic contact between somatic motor neuron and individual muscle fibre
45
excitation-contraction coupling
an action potential initiated in skeletal muscle fibre resulting in an increase in intracellular Ca2+