Lecture 2 Flashcards
functions of cell membranes
- physical isolation
- regulation of exchange with environment (semi-perm)
- communication between cell and environ.
- structural support
Cell membrane composed of…
lipid, protein, and small amount of carbs
T/F, Cell membranes are all created equally
F
The more metabolically active the membrane is the more….. it contains
protein
What 3 types of amphipathic lipids are found in cell membranes?
- phospholipids
- sphingolipids
- cholesterol
phospholipids
major lipid
sphingolipids
lipid rafts
cholesterol
increase viscosity and decreases permeability
extracellular surface of cell membrane contains…
glycoproteins and glycolipids
intergral proteins roles
- membrane receptors
- cell adhesion molecules
- transmember movement
- enzymes
- mediators of intracellular signalling
peripheral proteins role
- participate in intracellular signalling
- form submembraneous cytoskeleton
peripheral proteins attache to…
loosely to phospholipid head of intergral proteins
transmembrane proteins
integral proteins
lipid anchored proteins
associated with sphingolipids and anchor with sugar-phosphate chain
lipid anchored proteins and lipid rafts have…
high cholesterol content - therefore, more viscous regions
lipid rafts
contain an abundance of proteins important in cell signal transduction
two different lipid rafts
planar lipid rafts and caveolae
carbs in cell membrane include…
glycoproteins and glycolipid