GI 4 Flashcards

1
Q

Active transport of free H+ into the stomach lumen in exchange for K+ increases…

A

pH, drawing in H2O and CO2 in the cell

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2
Q

What can inhibit acid secretion?

A

intestinal hormones

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3
Q

Digestive enzyme secretion is stimulated by…

A

neural input and acid secretion

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4
Q

ECL-Histamine

A

activates H2 receptors on parietal cells to stimulate HCl secretion

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5
Q

parietal cell-intrinsic factor

A

forms a complex with vitamin B12 so it can be absorbed

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6
Q

D cell-somatostatin

A
  • negative feedback for acid secretion

- inhibits pepsinogen release

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7
Q

Music secretion is stimulated by…

A

parasympathetic input and irritation

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8
Q

HCO3- secretion stimulated by…

A

parasympathetic input and H+

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9
Q

peptic ulcer

A

A sore or break in the lining of the stomach or duodenum

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10
Q

What causes peptic ulcers and how can it be treated?

A
  • caused by excessive acid production or bacteria

- treated with non steroidal anti-inflammatory drugs (NSAIDS)

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11
Q

Major cause of peptic ulcers?

A

bacteria

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12
Q

What is the urea breath test

A

A test for diagnosing the presence of the ulcer-causing bacterium, H. pylori in the stomach.

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13
Q

Describe intestinal phase

A
  • food, fluids, and secretions enter small intestine
  • segmental and peristaltic contractions mix chyme with enzymes and expose nutrients to mucosal epithelium for absorption
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14
Q

What promotes motility?

A

parasympathetic innervation, gastrin, and cholecystokinin

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15
Q

What inhibits motility?

A

Sympathetic innervation

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16
Q

villi

A

increase surface area available for absorption and secrete mucus

17
Q

crypts

A

contain hormone and fluid secretory cells and stem cells (secrete ions and water)

18
Q

lacteals

A

tranport most fats to the lymph

19
Q

enterocytes

A

transport nutrients and ions

20
Q

Hepatic portal system

A

The liver contains a variety of enzymes that metabolize drugs and xenobiotics and clear them from blood stream before it can proceed to systemic circulation

21
Q

Intestinal secretions promote..

A

digestion

22
Q

Approximately ____L of secretions enter the lumen of the small intestine.

A

3.5L (along with 5.5L of food, fluid, and secretions)

23
Q

~ __L ABSORBED IN DUODENUM AND JEJUNUM

A

7.5L