GI 4 Flashcards
Active transport of free H+ into the stomach lumen in exchange for K+ increases…
pH, drawing in H2O and CO2 in the cell
What can inhibit acid secretion?
intestinal hormones
Digestive enzyme secretion is stimulated by…
neural input and acid secretion
ECL-Histamine
activates H2 receptors on parietal cells to stimulate HCl secretion
parietal cell-intrinsic factor
forms a complex with vitamin B12 so it can be absorbed
D cell-somatostatin
- negative feedback for acid secretion
- inhibits pepsinogen release
Music secretion is stimulated by…
parasympathetic input and irritation
HCO3- secretion stimulated by…
parasympathetic input and H+
peptic ulcer
A sore or break in the lining of the stomach or duodenum
What causes peptic ulcers and how can it be treated?
- caused by excessive acid production or bacteria
- treated with non steroidal anti-inflammatory drugs (NSAIDS)
Major cause of peptic ulcers?
bacteria
What is the urea breath test
A test for diagnosing the presence of the ulcer-causing bacterium, H. pylori in the stomach.
Describe intestinal phase
- food, fluids, and secretions enter small intestine
- segmental and peristaltic contractions mix chyme with enzymes and expose nutrients to mucosal epithelium for absorption
What promotes motility?
parasympathetic innervation, gastrin, and cholecystokinin
What inhibits motility?
Sympathetic innervation