Renal 3

Question 1

Regulated reabsorption allows kidneys to…

Answer 1

selectively return ions and water to the plasma to maintain homeostasis

Question 2

Filtrate in lumen and ECF initially have…

Answer 2

similar solutions conc.

Question 3

Most renal transport is…

Answer 3

transcellular

Question 4

______ transport is used to generate electrochemical, osmotic and concentration gradients for reabsorption

Answer 4

active

Question 5

Na+ is pumped out of the basolateral side of the cells by Na+K+-ATPase through active transport to…

Answer 5

prevent build up

Question 6

Secondary active transport of Na+

Answer 6

symport with glucose, amino acids, other organic metabolites

Question 7

How are urea nitrogenous waste products reabsorbed?

Answer 7

passive transport

Question 8

What is reabsorbed through endocytosis?

Answer 8

very small plasma proteins or peptides

Question 9

megalin

Answer 9

receptor binding plasma proteins that mediate endocytosis

Question 10

saturation

Answer 10

The max. rate of transport that occurs when all available carriers are occupied

Question 11

The majority of substances transported in the nephron use…

Answer 11

membrane proteins

Question 12

transport maximum

Answer 12

the transport rate at saturation

Question 13

The amount of glucose filtered depends on..

Answer 13

the plasma glucose conc.

Question 14

Reabsorption of glucose is proportional to..

Answer 14

plasma conc. until transport max is reached

Question 15

renal threshold

Answer 15

the plasma conc. of a solute when it first begins to appear in urine

Question 16

renal threshold occurs at…

Answer 16

transport max

Question 17

glycosuria or glycosuria

Answer 17

• glucose appearing in urine
• occurs with elevated blood glucose
• rare genetic disorder with reduced transporters

Question 18

secretion

Answer 18

transfer of molecules from the ECF into the lumen of the nephron

Question 19

organic anion transporters

Answer 19

tertiary active transport; broad range of products transported

Question 20

alpha-hetoglutarate (aKG)

Answer 20

by-product of the citric acid cycle

Question 21

probenecid

Answer 21

preferentially secret by the OAT transporter so it was given with penicillin to allow penicillin to stay in the body longer

Question 22

excretion=

Answer 22

filtration-reabsorption+secretion

Question 23

How do we directly look at filtration, reabsorption and secretion at the level of an individual nephron?

Answer 23

experimentally and analysis of urine and blood

Question 24

clearance

Answer 24

rate at which solute disappears from the body by excretion or metabolisms; noninvasive way to measure GFR

Question 25

clearance of X =

Answer 25

(mg/min)/(mg/mL)

Question 26

To most accurately calculate GFR we need to look at the clearance of...

Answer 26

a substance that is freely filtered and neither reabsorbed or secreted

Question 27

creatinine

Answer 27

commonly used to measure GFR and indicator of renal function

Question 28

net reabsorption

Answer 28

If filtration is greater than excretion

Question 29

net secretion

Answer 29

If excretion is greater than filtration

Question 30

Hi

Answer 30

GREAT JOB