GI 7 Flashcards
The use of penicillin based antibiotics can…
alter the normal bacterial flora and leaves you prone to infection by C. difficile
colitis
watery diarrhea, fever, nausea, and abdominal pain
lateral hypothalamus
hunger center
ventromedial hypothalamus
satiety center
glucostatic theory
glucose metabolism in the hypothalamus regulates food intake
lipostatic theory
signals from the bodies fat stores regulate food intake
leptin
released from adipocytes and regulates body mass by acting directly on neurons of the hypothalamus that decrease appetite and increase energy expenditure
Response to elevated leptin
- INHIBITION OF LATERAL FEEDING CENTER
- activation of PVN
Activation of PVN
- increased metabolic rate throughout the body
- increased body temp
Response to decreased leptin
- reduced activation of a-MSH and CART neurons
- activation of NPY and AgRP containing neurons (STIMULATION OF FEEDING CENTER)
Aside from social and cultural factors, short-term regulation of feeding behaviour depends on…
How long it has been since the last meal and how much we consumed at that time.
ghrelin
released by cells in the stomach in response to emptying
-ghrelin injection will stimulate food intake
Gastric distension and CCK both act on the NTS to…
stimulate the feeling of satiety
During the cephalic and gastric phase, increased insulin would…
cause a drop on blood glucose - driving hunger through activation of NPY/AgRP neurons
During the intestinal phase, the increased blood glucose/insulin….
Acts as a satiety signal activating aMSH/CART neurons
