Neuro 6 Flashcards
neurotransmitters are released from…
vesicles
large neurotransmitters are produced and packaged into vesicles at the ……
soma and transported (fast axonal)
small neurotransmitters are synthesized and packaged at….
the axon terminal (synthesized enzymes brought to terminal via slow axonal)
how are neurotransmitters released?
via Ca2+ mediated exocytosis
Pre-synaptic terminals contain…
a high conc. of voltage-gated Ca2+ channels
3 ways to inactivate neurotransmitters
- they return to axon terminals for reuse or transported into glial cells
- inactivated by enzymes
- they diffuse out of synaptic cleft
stronger stimuli mean…
more neurotransmitters
convergence
many presynaptic neurons converging to one or a small number of postsynaptic neurons
divergence
neurons branching and contact many different postsynaptic neurons
spatial summation
when currents from nearly simultaneous graded potentials of multiple neurons combine
Spatial summation can be….
excitatory and inhibitory
temporal summation
when two graded potentials from one presynaptic neuron occur close together
axo-axonic synapse
augment communication between pre and postsynaptic cell
presynaptic inhibition
inhibits neurotransmitter release
presynaptic facilitation
increases neurotransmitter release