Post-Transcriptional Regulation Flashcards
Post-Transcriptional Regulation occurs only in
Eukaryotes
What is important about Post-Transcriptional Regulation?
It protects mRNA from premature degradation before translation
What happens within Post-Transcriptional Regulation?
Spliceosome removes introns by binding to either side of intron, looping it into a circle, cleaving it off, and then ligating exons together
The 5’ Cap is a modification in which the
Phosphate end gets capped and converted into a 3’ end via 5’ to 5’ linkage
The 5’ Cap promotes
Ribosomal binding and the nuclear export of mRNA
The 3’ Poly A Tail is a modification in which
Adenine bases added
The 3’ Poly A Tail helps with
Transcription termination for RNA Pol
What catalyzes the Poly A tail
The Poly A Pol
What is RNA Editing?
RNA regulation that results in sequence variation and is catalyzed by various enzymes
RNA Editing is done via what enzymes?
- ADAR Enzymes
- CDAR Enzymes
What is the function of ADAR Enzymes?
They convert Adenosine residues to Inosine in mRNA molecule via hydrolytic deamination
What is the function of CDAR Enzymes?
They do deamination of cytosine to Uridine
