Amino Acids Flashcards
Histidine is an Amino Acid which exists in both
Protonated and deprotonated forms
Why is Histidine an Amino Acid found in the active site of a protein?
It can stabilize or destabilize structure
Proline is an Amino Acid that contains
A secondary amino group
Proline is an Amino Acid capable of
Disrupting the alpha helix pattern, introducing kinks
Glycine is an Amino Acid like Proline which is capable of
Disrupting the alpha helix pattern, introducing kinks
What is significant about Glycine?
It lacks a chiral Alpha Carbon
Cystine is an Amino Acid that contains
A Thiol group
What does Cystine form with other Cystines?
Disulfide bridges
What kind of environment are Thiols found in?
A reducing environment
Disulfide bridges are found in which environments?
Oxidizing environments
When is an Amino Acid protonated / positive charged?
When AA pKa > pH
When is an Amino Acid depronated?
When AA pKa < pH
What kind of environment is the extracellular of the cell?
Oxidizing environment
In an L configuration, the Amino Acid contains a
NH2 at the left
In a D configuration, the Amino Acid contains a
NH2 at the right
