Enzymes Flashcards

1
Q

Enzymes are Biological Catalysts that create

A

Conditions that allow for faster biochemical reactions

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2
Q

Carbonic Anhydrase is an enzyme found in the

A

Human blood and saliva

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3
Q

What is the function of Carbonic Anhydrase?

A

Makes carbonic acid turn into CO2 and H2O quickly

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4
Q

What are Catalytic strategies used by enzymes to catalyze reactions?

A
  • Acid/Base Catalysis
  • Covalent Catalysis
  • Metal Ion Catalysis
  • Catalysis by Approximation
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5
Q

Acid/Base Catalysis is a strategy in which enzymes

A

Help move protons around

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6
Q

Covalent Catalysis is a strategy in which enzymes

A

Form covalent bonds with other molecules and allow for electron transfer

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7
Q

Metal Ion catalysis allows for enzymes to

A

Create a stabilizing charge

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8
Q

Catalysis by Approximation allows for enzymes to

A

Force two molecules to collide in the correct orientation

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9
Q

The TCA cycle is a series of

A

Different biochemical reactions in carbon metabolism

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10
Q

What kind of energy is generally more stable?

A

Lower energy

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11
Q

Enzymes work by

A

Lowering the AE, stabilizing the reaction

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12
Q

The highest point on the graph is generally the

A

Transition state

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13
Q

By reason the transition state is the highest point, it displays the most

A

Instability

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14
Q

What is the Free Energy of Activation (Ea)?

A

The difference between energy level of where we start and transition state / free energy of activation

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15
Q

The Free Energy of Activation (Ea) determines

A

How quickly a reaction will go

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16
Q

What is the Standard Free Energy Change (Erxn)?

A

Difference in energy between beginning energy level and final energy level

17
Q

How does the energy state differ throughout a spontaneous reaction?

A

The products will have a lower state of energy compared to the reactants

18
Q

How is the AE of a catalyzed reaction?

A

Smaller / Lower

19
Q

How is the transition state of a catalyzed reaction?

A

Lower

20
Q

What are substrates?

A

Any molecules that enzymes will act on

21
Q

What is the function of substrates?

A

They turn into reactants within the reaction

22
Q

Enzymes have active sites which are locations where

A

Substrates bind

23
Q

Enzyme reactions happen at the

A

Active site

24
Q

What is significant about the active sites?

A

They are unique, only binding to certain substrates

25
Q

An induced fit is one in which

A

Both enzyme and substrate change shape in order to mold together

26
Q

What happens at the transition state of a reaction?

A

The bond between the substrate and enzyme is the tightest

27
Q

What happens when an enzyme reaction is completed?

A

The substrate is cut in half by the enzyme

28
Q

Allosteric Binding is when

A

Some enzymes are capable of binding to more than 1 substrate

29
Q

What is the function of an inhibitor?

A

It can bind enzyme at different location than enzyme’s active site

30
Q

Inhibitors are capable of changing the shape of an enzyme, which

A

Affects an enzyme’s ability to catalyze reactions

31
Q

What is an Allosteric site?

A

A site outside of the binding site

32
Q

Amylase is an enzyme which best works at

A

pH = 7

33
Q

Pepsin is an enzyme which breaks down

A

Proteins into peptides

34
Q

Pepsin is an enzyme which best works at

A

pH = 2