Blood Flashcards
How much of the blood is plasma?
90%
What is Albumin?
A plasma protein that prevents leakage in blood vessels
What is Fibrinogen?
Plasma protein that allows blood protein
Polycythemia occurs when
Hematocrit is high
Anemia occurs when
Hematocrit is low
Oxygen moves from the alveoli to
Red blood cells
What make up blood vessel walls?
Endothelial cells
What block the damage within blood vessels?
Platelets
What is found on the outside of blood vessels?
Collagen
What is the function of collagen?
It interacts with platelets, causing for them to stick together
What strengthens the platelet plug?
Fibrin
Fibrinogen becomes Fibrin when it interacts with
Tissue factor proteins of the endothelium
Thrombin also converts
Fibrin into Fibrinogen
Thrombin is activated from
Prothrombin
How long do RBCs last?
120 days
Erythropoiesis starts from a precursor cells that divides via
Mitosis several times, with the nucleus being lost over time
Platelets are fragments of cells that come from
Megakaryocytes
What are Megakaryocytes?
Big cells with cytoplasm
What is the function of the Spleen?
They recognize old blood cells and break them via monocytes
The Spleen reuses
Parts of the RBC
Some of the breakdown of platelets and RBC also happens in the
Liver
When there is low Oxygen, the body produces
Erythropoietin
Erythropoietin tells the bone marrow to
Produce blood cells
Erythropoietin is released by the
Kidney
Which cell is the precursor to all blood cells in the body?
The Pluripotent cell
The Pluripotent cell gives rise to
2 different lineages
What are the two different lineages of blood cells?
Myeloid + Lymphoid
The Myeloid lineage gives rise to
- RBCs
- Megakaryocyte
- Immune Cells
- Macrophages
- Mast Cells
The Lymphoid lineage gives rise to
- T Cells
- B Cells
Mast cells function to
Release histamine
