Central Dogma Flashcards

1
Q

Reverse transcription is when

A

Information travels “backwards” from RNA to DNA

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2
Q

Reverse transcriptase generates cDNA from a copy of

A

RNA template

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3
Q

Retroviruses replicate via

A

Reverse transcriptase

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4
Q

What happens once viruses reverse transcribe their RNA genome back into the DNA?

A

The genome is integrated + replicated into the host genome

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5
Q

In RNA viruses, genetic material is stored as

A

RNA

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6
Q

How do viruses use their genetic material?

A

The virus hosts use RNA of the replication machinery as mRNA and translate that into protein

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7
Q

Noncoding RNA is a functional RNA molecule that can

A

Directly perform functions

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8
Q

Epigenetics are

A

Heritable changes in gene activity

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9
Q

What allows for DNA modification to show different phenotypes?

A

Epigenetics

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10
Q

Epigenetics allows transcription of only

A

Certain genes of the genome

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11
Q

Proteins are formed from the

A

Folding of polypeptide chains (which are formed by peptide bonds)

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12
Q

Peptide Bonds are formed by the

A

Relationship between carboxyl group of one AA and Amino of another AA

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13
Q

How are peptide bonds?

A

Rigid and planar bonds

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14
Q

Peptide bonds are bonds that can experience

A

Resonance stabilization

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15
Q

Peptide bonds can be broken via

A

Hydrolysis with the help of either strong acids or protease enzymes

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16
Q

What is significant about peptide bond acid-catalyzed hydrolysis?

A

The strong acids are nonspecific, so all bonds will break in a given solution

17
Q

What is significant about peptide bond protease enzymes hydrolysis?

A

Proteolysis allows for the choosing of which bonds breaks