Biosignaling Flashcards
What is the role of the membrane receptor?
To aid communication between a cell and its environment
A membrane receptor aids in the cellular response to the
External environment
What is a ligand?
A molecule that attaches to a receptor, triggering changes within the cell
Medications typically act as
Ligands for receptors
In which type of cell are ligand-gated ion channels most commonly found?
Cells that need to respond quickly to external stimuli
Cells that respond to mechanic forces typically possess
Stretch-activated ion channels
What is an example of a cell that displays xtretch-activated ion channels due to mechanic forces?
Cardiac cells
Terminally differentiated cells are comprised of
Multiple cell types
The ligand-gated ion channel allows for
A rapid response to a stimulus
Allosteric binding is an important feature of
Ligand-gated ion channels
Which receptors respond to deformations in the cell membrane?
Stretch receptors
How do ligand-gated ion channels react?
Quickly
Adenylate cyclase is an enzyme that is activated when
GTP interacts with it
What do receptor tyrosine kinases initiate?
Intracellular signaling cascades
Once phosphorylated, the intracellular segment of a receptor tyrosine kinase
Allows docking of intracellular proteins involved in signal transduction