Cell Cycle Phases Flashcards

1
Q

The Cell Cycle consists of

A

Interphase + Mitosis

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2
Q

Interphase pertains to

A

Cell growth (no division)

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3
Q

Most cells are found in which phase of the cycle?

A

Interphase

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4
Q

What are the parts of interphase?

A
  • G1
  • S
  • G2
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5
Q

G1 is the growth phase which is also the

A

Longest phase

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6
Q

What happens during the G1 phase?

A

Extra organelles like ribosomes + proteins are produced

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7
Q

After G1, cells can go to either

A

G0 or S

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8
Q

Which cyclins are produced during G1?

A

CycE or CycD

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9
Q

S Phase is the Synthesis phase in which there is

A

DNA replication of 23 pairs

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10
Q

Which cyclins are produced during S phase?

A

Cyclin A, which binds with CDK to activate DNA replication

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11
Q

G2 is the growth phase in which the cell

A

Prepares for mitosis

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12
Q

What happens during the G2 phase?

A

Microtubules are made

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13
Q

Which cyclins are produced during G2 phase?

A

Cyclin B to bond with CDK 1

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14
Q

The first checkpoint is found between

A

G1 and S phase

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15
Q

DNA replication is not inhibited when

A

CDK binds to the Cyclins E and D

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16
Q

Second checkpoint is found between

A

G2 and mitosis

17
Q

CDK gets activated when paired with

A

Cyclins

18
Q

What is required in order to pass checkpoints?

A

Cyclin proteins need to present to block any proteins which may interfere with DNA synthesis or replication

19
Q

PB3 is a protein that functions to

A

Block cell cycle progression

20
Q

P21 is a protein that

A

Inhibits CDK

21
Q

Rb + P53 are tumor-suppressor genes, so a defect can result in

A

Cancer

22
Q

Most of the cell’s life and DNA replication occurs during

A

Interphase

23
Q

How are chromosomes in interphase?

A

Not tightly bound, rather in chromatin form