Eukaryotic Cells Flashcards

1
Q

Where does transcription occur?

A

In the nucleus

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2
Q

The nucleus is surrounded by which two membranes?

A

Inner + Outer

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3
Q

What is the fluid in the nucleus?

A

Nucleoplasm

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4
Q

What allows for the exchange of materials both into and out of the nucleus?

A

Nuclear pores

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5
Q

How are nuclear pores selective with what can be transported?

A

They need to recognize signal in order to transport

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6
Q

The Nucleolus is the center of the Nucleus and is the site of

A

Ribosome assembly

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7
Q

How does the Nucleolus allow for Ribosome assembly?

A

It contains rRNA that is assembled with proteins to become ribosomes

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8
Q

The nucleus membrane is also connected with

A

Endoplasmic Reticulum

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9
Q

The Nuclear Envelope is composed of

A

Inner + Outer membranes + nuclear pores

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10
Q

Mitochondria is the site of

A

Cellular respiration

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11
Q

What happens in the Mitochondria?

A

Glucose (Pyruvate) is transformed into ATP

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12
Q

The Outer membrane of the Mitochondria is made of a

A

Lipid bilayer permeable to small molecules

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13
Q

The Inner membrane of the Mitochondria is made of a

A

Lipid bilayer not permeable to small molecules

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14
Q

The Inner membrane has folds called

A

Cristae

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15
Q

What is the function of cristae?

A

They increase SA, more room for cellular respiration

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16
Q

Where does ETC happen in the mitochondria?

A

In the inner membranes

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17
Q

Describe inner membrane of the Mitochondria

A
  • Studded with enzymes

- More acidic due to H+ ions

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18
Q

Mitochondria having its own genome allows for it to

A
  • Make some proteins for ETC

- Produce parts of protein synthase

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19
Q

The mitochondria has its own system of

A

Transcription and translation

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20
Q

The ER is a

A

Folded, continuous membranes

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21
Q

What is the site of protein synthesis?

A

ER

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22
Q

The ER sends proteins to the

A

GA

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23
Q

What is the site of protein synthesis?

24
Q

What happens to the proteins synthesized by the RER?

A
  • Secreted into EC environment
  • Become integral proteins
  • Might remain in the ER, GA, or in lysosomes
25
RER proteins that become secreted or become part of the cell membrane follow which pathway?
The secretory pathway
26
What is the secretory pathway?
The pathway a protein takes from when it’s synthesized until when it leaves the cell / becomes part of cell membrane
27
When does a protein follow the secretory pathway?
When it receives a signal sequence, which is detected early on in translation
28
What is the function of the SER?
It synthesizes lipids, metabolizes carbs, and detoxifies drugs
29
The GA is found near the
ER
30
What is the GA?
Groups of sacs stacked together
31
The modified RER proteins are sent to the
GA
32
What is the function of the GA?
- It sorts and sends proteins to proper destinations | - Synthesizes certain molecules that need to be secreted in the cell
33
Where does the vesicle merge into the GA?
At the cis-stack
34
In the GA, the protein undergoes modifications and is transferred into the
Medial stack
35
What happens when the protein is in the trans-stack of the GA?
It can leave and can either go to cell membrane or into a lysosome
36
What is the function of the Lysosome?
It digests molecules + substances
37
What are the two functions of the Lysosome?
- Autophagy | - Crinophagy
38
What is Autophagy?
Lysosomes digest organelles part of the cell itself
39
Macrophages of the immune system display
Autophagy
40
Crinophagy is when
Lysosomes digest excess secretory products
41
What is the function of the Peroxisome?
It breaks and detoxifies lipids
42
Peroxisome isolates peroxides and uses catalase to
Break it into water and oxygen
43
What are introns?
Bits of DNA that are cut out by molecules found in the nucleus
44
What is differential splicing?
Different combinations of introns can be cut out to form variations on a protein
45
Both prokaryotes and eukaryotes have repressors which function to
- Bind DNA at promoter site | - Regulate transcription
46
Mitochondrial DNA disorders are transferred through the
Maternal line
47
What are Gangliosides?
Glycolipids attached to acids
48
Microfilaments are made out of
Actin
49
What is the function of Microfilaments?
They work with myosin filaments to contract the cell
50
Microtubules are components of
Flagella and Cilia
51
What is the function of Intermediate filaments?
They help the cell retain its shape in the face of mechanical stress
52
What is the function of the sarcoplasmic reticulum?
It helps store calcium
53
The smooth endoplasmic reticulum in muscle cells allows for
Efficient contractions
54
Where are proteins made?
- Ribosomes | - On Rough ER
55
Microtubules are involved in
- Cell structure | - Motility
56
Microtubules can be found in
Mitotic spindles