DNA Flashcards

1
Q

DNA Pol adds nucleotides to the

A

3’ end

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2
Q

In what direction does DNA Pol extend in?

A

5’ to 3’

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3
Q

What is the first AA in polypeptide chain during translation?

A

Formal Meth

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4
Q

Describe DNA Pol I?

A
  • Removes RNA primer

- Has exonuclease activity

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5
Q

What happens within the Mismatch Repair System?

A

There are many proteins which recognize a mismatch in the DNA and will cut the incorrect base

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6
Q

What comes in to remove the incorrect nucleotide?

A

An exonuclease

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7
Q

What comes in and adds a new and correct nucleotide within the Mismatch Repair System?

A

A DNA Pol

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8
Q

UV Ray Damage creates

A

Pyrimidine Dimers

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9
Q

How does UV Ray Damage create dimers?

A

It causes for two identical bases to stick together, getting the identical bases to stick together

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10
Q

Pyramidine Dimers can be fixed via

A

NER

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11
Q

How does NER work?

A
  • Endonuclease removes dimers
  • DNA Pol will come and bring correct nucleotides
  • Ligase will connect everything
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12
Q

What is a mismatch capable of?

A

Distorting DNA

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13
Q

What happens to the Adenines in bacterial parental DNA?

A

Adenines will be methylated

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14
Q

Endogenous DNA Damages can occur due to

A

Reactive O2 species

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15
Q

Exogenous DNA Damages can occur due to

A
  • UV Rays
  • Gamma Rays
  • X Rays
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16
Q

What is a normal byproduct of ETC in the mitochondria?

A

Reactive O2 species

17
Q

Genetic material is lost from the telomeres when

A

Okazaki fragments are joined

18
Q

In what direction is DNA synthesized when catalyzed by either DNA polymerase or reverse transcriptase?

A

5’ –> 3’

19
Q

What cleave specific sequences of DNA?

A

Endonucleases